Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PARP1 | P09874 | 3/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.33 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | CCR4 | P51679 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL701908 | 0.81 | KDM4E (0.37) | KDM4EMEN1HTTKMT2APARP1 | |
| SCHEMBL701907 | 0.81 | KDM4E (0.37) | KDM4EMEN1HTTKMT2APARP1 | |
| SCHEMBL650830 | 0.80 | HPGD (0.42) | KDM4EMEN1HTTKMT2ANPC1 | |
| SCHEMBL708157 | 0.78 | SYK (0.35) | KMT2ANUAK1PARP1HRH3 | |
| SCHEMBL650903 | 0.78 | NOS3 (0.34) | — | |
| SCHEMBL711443 | 0.77 | KDM4E (0.39) | KDM4EPARP1HRH3KDRHPGD | |
| SCHEMBL705496 | 0.74 | PIK3CA (0.37) | PARP1PDE3BPDE3AKDR | |
| SCHEMBL649545 | 0.73 | HPGD (0.44) | KDM4EMEN1KMT2ANPC1RAB9A | |
| SCHEMBL708159 | 0.73 | PIK3CA (0.35) | PARP1 | |
| SCHEMBL708508 | 0.72 | UTS2R (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2423204-A1 | THIAZOLIDINONE DERIVATIVE | SBI Biotech Co., Ltd. (JP) | 2012-02-29 | — | — | EP | disclosed |