Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ASPH | Q12797 | 11/20 | 0.39 |
| ▸ | KDM8 | Q8N371 | 10/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.39 |
| ▸ | RIOX2 | Q8IUF8 | 7/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12861007 | 0.69 | PTGS2 (0.44) | KDM4ELMNANPC1ALDH1A1SMN1; SMN2 | |
| SCHEMBL7104473 | 0.69 | ALOX15 (0.39) | LMNANPC1RAB9AALDH1A1 | |
| SCHEMBL9318375 | 0.68 | ASPH (0.56) | ASPHKDM8KDM4ERIOX2LMNA | |
| SCHEMBL2960866 | 0.64 | TP53 (0.50) | KDM4EALDH1A1SMN1; SMN2 | |
| SCHEMBL3631706 | 0.63 | ALDH1A1 (0.48) | KDM4ELMNAALDH1A1HCAR2 | |
| SCHEMBL27581275 | 0.62 | KDM4E (0.52) | KDM4ELMNAALDH1A1 | |
| SCHEMBL19857498 | 0.61 | GABRP (0.66) | ASPHKDM8KDM4ERIOX2LMNA | |
| SCHEMBL31220850 | 0.61 | KDM4E (0.47) | ASPHKDM8KDM4ELMNAP4HTM | |
| SCHEMBL15043886 | 0.61 | TSHR (0.51) | ASPHKDM8KDM4ELMNAP4HTM | |
| SCHEMBL5252545 | 0.61 | TSHR (0.51) | ASPHKDM8KDM4EP4HTMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339665-A1 | NITRODERIVATIVES AS DRUGS FOR DISEASES HAVING AN INFLAMMATORY BASIS | Nicox S.A. (FR) | 2003-09-03 | — | — | EP | disclosed |
| WO-2002030866-A1 | NITRODERIVATIVES AS DRUGS FOR DISEASES HAVING AN INFLAMMATORY BASIS | NICOX S.A. (FR) | 2002-04-18 | — | — | WO | disclosed |