Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERCC1 | P07992 | 1/20 | 0.42 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.42 |
| ▸ | MMP1 | P03956 | 2/20 | 0.41 |
| ▸ | HTR7 | P34969 | 2/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | GGPS1 | O95749 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | PPIB | P23284 | 1/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7103182 | 0.89 | NR1H2 (0.43) | MMP1HTR7OPRM1MMP2MMP9 | |
| SCHEMBL7103454 | 0.82 | HTR7 (0.46) | HTR7OPRM1OPRD1OPRK1CYP3A4 | |
| SCHEMBL7106093 | 0.77 | ERCC1 (0.48) | ERCC1ERCC4MMP1MMP2MMP9 | |
| SCHEMBL19552539 | 0.71 | KMT2A (0.43) | OPRM1CYP2C19 | |
| Hydrochloric Acid SCHEMBL19552415 | 0.70 | KMT2A (0.42) | OPRM1SMN1; SMN2CYP2C19 | |
| SCHEMBL7106098 | 0.70 | OPRK1 (0.53) | ERCC1ERCC4MMP1MMP2MMP9 | |
| SCHEMBL1525284 | 0.69 | SMN1; SMN2 (0.54) | ERCC1ERCC4OPRM1OPRL1MMP8 | |
| SCHEMBL4388189 | 0.69 | ERCC1 (0.53) | ERCC1ERCC4MMP8SMN1; SMN2CYP1A2 | |
| SCHEMBL7103181 | 0.68 | CYP3A4 (0.45) | ERCC1ERCC4MMP1MMP2MMP9 | |
| SCHEMBL17107769 | 0.68 | MMP8 (0.55) | ERCC1ERCC4OPRM1OPRL1MMP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1055665-B1 | 3-(3-Hydroxyphenyl)-3-amino-propionamide derivatives | PFIZER PROD INC (US) | 2003-10-22 | — | — | EP | disclosed |
| EP-1055665-A1 | 3-(3-Hydroxyphenyl)-3-amino-propionamide derivatives | Pfizer Products Inc. (US) | 2000-11-29 | — | — | EP | disclosed |