Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 9/20 | 0.76 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.76 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | PTGIR | P43119 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.42 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.41 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7107673 | 0.95 | OPRK1 (0.77) | OPRK1OPRD1CACNA1HPOLBSMN1; SMN2 | |
| SCHEMBL7101012 | 0.86 | OPRK1 (1.00) | OPRK1OPRD1POLB | |
| SCHEMBL7106987 | 0.81 | OPRK1 (0.73) | OPRK1OPRD1MTNR1AMTNR1B | |
| SCHEMBL18978191 | 0.70 | KMT2A (0.42) | POLBMEN1KMT2ASMN1; SMN2PTGIR | |
| SCHEMBL14533685 | 0.69 | AOC3 (0.46) | POLBMEN1KMT2ASMN1; SMN2MTNR1A | |
| SCHEMBL20103399 | 0.69 | FFAR1 (0.57) | POLBFFAR1 | |
| SCHEMBL7102313 | 0.68 | OPRK1 (1.00) | OPRK1OPRD1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5524760 | 0.67 | PTGIR (0.53) | MEN1KMT2ASMN1; SMN2PTGIRMTNR1A | |
| SCHEMBL5524757 | 0.67 | PTGIR (0.53) | MEN1KMT2ASMN1; SMN2PTGIRMTNR1A | |
| SCHEMBL2404817 | 0.66 | L3MBTL1 (0.53) | OPRK1POLBMEN1KMT2AMTNR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1055665-B1 | 3-(3-Hydroxyphenyl)-3-amino-propionamide derivatives | PFIZER PROD INC (US) | 2003-10-22 | — | — | EP | disclosed |
| EP-1055665-A1 | 3-(3-Hydroxyphenyl)-3-amino-propionamide derivatives | Pfizer Products Inc. (US) | 2000-11-29 | — | — | EP | disclosed |