Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 9/20 | 0.73 |
| ▸ | OPRD1 | P41143 | 4/20 | 0.58 |
| ▸ | CASR | P41180 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 3/20 | 0.50 |
| ▸ | MTNR1B | P49286 | 3/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7102313 | 0.85 | OPRK1 (1.00) | OPRK1OPRD1 | |
| SCHEMBL7106587 | 0.81 | OPRK1 (0.76) | OPRK1OPRD1MTNR1AMTNR1B | |
| SCHEMBL7107673 | 0.78 | OPRK1 (0.77) | OPRK1OPRD1MTNR1AMTNR1B | |
| SCHEMBL15471187 | 0.73 | MMP13 (0.65) | — | |
| SCHEMBL7101712 | 0.72 | OPRK1 (1.00) | OPRK1OPRD1 | |
| SCHEMBL14201168 | 0.71 | MMP13 (0.62) | — | |
| SCHEMBL7106526 | 0.71 | OPRK1 (1.00) | OPRK1OPRD1MTNR1A | |
| SCHEMBL9238860 | 0.71 | TACR1 (0.81) | — | |
| SCHEMBL619351 | 0.70 | MMP13 (0.60) | — | |
| SCHEMBL14229091 | 0.70 | RIPK1 (0.64) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1055665-B1 | 3-(3-Hydroxyphenyl)-3-amino-propionamide derivatives | PFIZER PROD INC (US) | 2003-10-22 | — | — | EP | disclosed |
| EP-1055665-A1 | 3-(3-Hydroxyphenyl)-3-amino-propionamide derivatives | Pfizer Products Inc. (US) | 2000-11-29 | — | — | EP | disclosed |