SCHEMBL309042

SCHEMBL309042

C#Cc1ccc(Oc2ccccc2)cc1

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 9/20 0.57
TSHR P16473 1/20 0.57
NR1H2 P55055 1/20 0.50
BAX Q07812 1/20 0.50
MAOA P21397 1/20 0.50
PLA2G2A P14555 1/20 0.47
CA1 P00915 1/20 0.45
CA2 P00918 1/20 0.45
HAO1 Q9UJM8 1/20 0.44
GSTP1 P09211 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2187923 0.90 HAO1 (0.44) LTA4HTSHRCA1CA2HAO1
SCHEMBL7038781 0.83 HAO1 (0.41) LTA4HTSHRCA1CA2HAO1
SCHEMBL3840668 0.83 HAO1 (0.46) LTA4HTSHRCA1CA2HAO1
SCHEMBL11121987 0.81 CES2 (0.53) HAO1
SCHEMBL5689227 0.80 LTA4H (0.50) LTA4HTSHRNR1H2BAXCA1
SCHEMBL6287635 0.80 LTA4H (0.63) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL9658226 0.79 ALDH1A1 (0.64) LTA4HTSHRMAOA
SCHEMBL7106722 0.79 MAOA (0.52) LTA4HMAOACA2HAO1
SCHEMBL4552830 0.79 LTA4H (0.54) LTA4HCA1CA2HAO1
SCHEMBL7035102 0.79 MEN1 (0.64) LTA4HNR1H2BAXCA2HAO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 224 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814462-B2 Functionalized cyclic polymers and methods of preparing same UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2023-11-14 US claimed
US-20220056167-A1 Functionalized Cyclic Polymers and Methods of Preparing Same NATIONAL SCIENCE FOUNDATION 2022-02-24 US claimed
WO-2020223672-A1 FUNCTIONALIZED CYCLIC POLYMERS AND METHODS OF PREPARING SAME UNIVERSITY OF FLORIDA RESEARCHFOUNDATION, INC. (US) 2020-11-05 WO claimed
EP-1551834-B1 SUBSTITUTED QUINAZOLINONE COMPOUNDS NOVARTIS VACCINES & DIAGNOSTIC (US) 2010-08-25 EP claimed
EP-1299354-B1 FACTOR VIIA INHIBITORY (THIO)UREA DERIVATIVES, THEIR PREPARATION AND THEIR USE SANOFI AVENTIS DEUTSCHLAND (DE) 2009-07-22 EP claimed
EP-1417190-B1 SUBSTITUTED PIPERAZINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR AMGEN INC (US) 2008-10-22 EP claimed
EP-1416933-B1 SUBSTITUTED PIPERIDINES AS MODULATORS OF THE MELANOCORTIN RECEPTOR AMGEM INC (US) 2008-01-02 EP claimed
EP-0998454-B1 METALLOPROTEINASE INHIBITORS BRITISH BIOTECH PHARM (GB) 2003-03-26 EP claimed
US-20260125371-A1 METHOD FOR INHIBITING CLOSTRIDIOIDES DIFFICILE SPORE GERMINATION UNIVERSITY OF NOTRE DAME DU LAC (US) 2026-05-07 US disclosed
EP-4602037-A1 METHOD FOR INHIBITING CLOSTRIDIOIDES DIFFICILE SPORE GERMINATION University of Notre Dame du Lac (US) 2025-08-20 EP disclosed
WO-2025104079-A1 SALICYLIC ACID AND PICOLINIC ACID DERIVATIVES AS INHIBITORS OF ENERGY COUPLING FACTOR (ECF) TRANSPORTERS FOR THE TREATMENT OF BACTERIAL INFECTIONS Helmholtz-Zentrum für Infektionsforschung GmbH (DE) 2025-05-22 WO disclosed
US-20250122133-A1 Selective Transition Metal Catalyzed Deuterium Incorporation Into Alkyne and Alkene Functionalities MARQUETTE UNIVERSITY 2025-04-17 US disclosed
US-20250115691-A1 METHOD OF FORMING PATTERNS SAMSUNG SDI CO LTD (KR) 2025-04-10 US disclosed
US-12063929-B2 3′-alkynyl abscisic acid derivatives as ABA antagonists UNIVERSITY OF SASKATCHEWAN (CA) 2024-08-20 US disclosed
CN-87103400-A The ethynyl thiophne pesticides that 2-replaces 1988-04-06 CN disclosed
US-4301313-A ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANALGESICS ELI-LILLY AND COMPANY (US) 1981-11-17 US disclosed
US-4226887-A P-BIPHENYLYLACETYLENE ELI LILLY AND COMPANY (US) 1980-10-07 US disclosed
US-4178428-A POLYACETYLENES THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE AIR FORCE (US) 1979-12-11 US disclosed
US-3991212-A PHENYLACETYLENE COMPOUNDS ELI LILLY AND COMPANY (US) 1976-11-09 US disclosed
US-3939278-A Phenoxyphenyl-acetylenes and thio analogues thereof as antithrombotic agents ELI LILLY AND COMPANY (US) 1976-02-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250122133-A1 Selective Transition Metal Catalyzed Deuterium Incorporation Into Alkyne and Alkene Functionalities HDHD5, DDT, AHR LTA4H 2222/4885TSHR 2408/4885NR1H2 405/4885
US-20260125371-A1 METHOD FOR INHIBITING CLOSTRIDIOIDES DIFFICILE SPORE GERMINATION CYP8B1, SPOUT1, O60361 LTA4H 387/4885TSHR 2142/4885NR1H2 372/4885
US-12063929-B2 3′-alkynyl abscisic acid derivatives as ABA antagonists AGL, ACSL3, ACSL1 LTA4H 259/4885TSHR 4375/4885NR1H2 1610/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.