Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | KCNA5 | P22460 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 5/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 5/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.33 |
| ▸ | HRH1 | P35367 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | TTK | P33981 | 1/20 | 0.33 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.33 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.33 |
| ▸ | MMP1 | P03956 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7061210 | 0.69 | SMN1; SMN2 (0.42) | CHRM2SMN1; SMN2MEN1GAAKMT2A | |
| SCHEMBL5754895 | 0.68 | HRH3 (0.48) | CYP2C19CNR1MEN1KMT2AALDH1A1 | |
| SCHEMBL7110560 | 0.67 | LMNA (0.35) | KCNA5SMN1; SMN2ALDH1A1MAPTKDM4E | |
| SCHEMBL23689568 | 0.63 | TSHR (0.48) | CYP2C19KCNA5TSHRCHRM2CHRM4 | |
| SCHEMBL10203032 | 0.63 | TSHR (0.48) | CYP2C19KCNA5TSHRCHRM2CHRM4 | |
| SCHEMBL7451904 | 0.62 | KCNA5 (0.46) | CYP2C19KCNA5TSHRCHRM2SMN1; SMN2 | |
| SCHEMBL7595164 | 0.62 | TSHR (0.49) | CYP2C19KCNA5TSHRCHRM2CHRM4 | |
| SCHEMBL21742093 | 0.61 | KCNA5 (0.45) | KCNA5TSHRCHRM2SMN1; SMN2MEN1 | |
| SCHEMBL5373022 | 0.61 | ADH1B (0.42) | SMN1; SMN2MEN1GAAKMT2ACYP3A4 | |
| SCHEMBL29770925 | 0.61 | ALDH1A1 (0.42) | CYP2C19TSHRSMN1; SMN2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030153571-A1 | Method and composition for the treatment of pain | ASTRAZENECA AB (SE) | 2003-08-14 | — | — | US | disclosed |
| EP-1244453-A1 | METHOD AND COMPOSITION FOR THE TREATMENT OF PAIN | AstraZeneca AB (SE) | 2002-10-02 | — | — | EP | disclosed |
| WO-2001047524-A1 | METHOD AND COMPOSITION FOR THE TREATMENT OF PAIN | ASTRAZENECA AB (SE) | 2001-07-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030153571-A1 | Method and composition for the treatment of pain | OPRK1, ACHE, OPRL1 | CYP2C19 1763/4885KCNA5 2557/4885TSHR 3256/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.