Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.40 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 14/20 | 0.37 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.37 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.37 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5267504 | 0.92 | HRH3 (0.43) | HRH3SMYD3P2RX3P2RX2SMN1; SMN2 | |
| SCHEMBL5673329 | 0.84 | PIK3CD (0.53) | PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL5271540 | 0.78 | GPR119 (0.52) | PIK3CDP2RX3P2RX2 | |
| SCHEMBL5266004 | 0.75 | SCD5 (0.35) | HMOX1 | |
| SCHEMBL17823854 | 0.74 | P2RX3 (0.55) | P2RX3P2RX2 | |
| SCHEMBL8083989 | 0.74 | NOS1 (0.40) | HRH3SMYD3P2RX3P2RX2SMN1; SMN2 | |
| SCHEMBL28930197 | 0.73 | PIK3CD (0.45) | HRH3HMOX1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL28930198 | 0.73 | PIK3CD (0.45) | HRH3HMOX1PIK3CDPIK3CAPIK3CB | |
| SCHEMBL1739282 | 0.73 | EPHX2 (0.52) | HMOX1RIPK1 | |
| SCHEMBL17654137 | 0.72 | GLS (0.45) | HMOX1SMN1; SMN2RIPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347990-A2 | PEPTIDE MIT INHIBIERENDER AKTIVITÄT ZUR PRODUKTION VON STICKSTOFFMONOXID | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-10-01 | — | — | EP | disclosed |
| WO-2002055541-A2 | PEPTIDES HAVING INHIBITING ACTIVITY ON THE PRODUCTION OF NITRIC OXIDE | FUJISAWA PHARMACEUTICAL CO (JP) | 2002-07-18 | — | — | WO | disclosed |