Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.58 |
| ▸ | TP53 | P04637 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | TSHR | P16473 | 2/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | ALDH5A1 | P51649 | 1/20 | 0.53 |
| ▸ | ABAT | P80404 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.53 |
| ▸ | CA2 | P00918 | 1/20 | 0.53 |
| ▸ | CA9 | Q16790 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11197700 | 0.92 | MAPK1 (0.50) | SMN1; SMN2ALDH1A1MAPK1GPR35TP53 | |
| SCHEMBL8159792 | 0.85 | ALDH1A1 (0.55) | SMN1; SMN2ALDH1A1MAPK1GPR35TP53 | |
| SCHEMBL21695808 | 0.81 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1MAPK1GPR35TP53 | |
| SCHEMBL21695800 | 0.81 | ALDH1A1 (0.50) | SMN1; SMN2ALDH1A1MAPK1GPR35TP53 | |
| SCHEMBL15847135 | 0.81 | MAPK1 (0.50) | SMN1; SMN2ALDH1A1MAPK1GPR35TP53 | |
| 2,4-Dinitrophenol SCHEMBL29185017 | 0.76 | GPR35 (0.96) | SMN1; SMN2ALDH1A1MAPK1GPR35TP53 | |
| SCHEMBL2801920 | 0.76 | GPR35 (0.62) | SMN1; SMN2ALDH1A1MAPK1GPR35TP53 | |
| SCHEMBL6031674 | 0.75 | MAPK1 (0.67) | SMN1; SMN2ALDH1A1MAPK1GPR35TP53 | |
| SCHEMBL69947 | 0.75 | MAPK1 (0.67) | SMN1; SMN2ALDH1A1MAPK1GPR35TP53 | |
| SCHEMBL29502912 | 0.75 | MAPK1 (0.67) | SMN1; SMN2ALDH1A1MAPK1GPR35TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1216851-C | Process for producing bis (4-hydroxy-3-nitrophenyl) compound | NIPPON KAYAKU KK (JP) | 2005-08-31 | — | — | CN | disclosed |
| US-6608233-B2 | Nitrating a bis(4-hydroxyphenyl) bonded to each other or through an electron-donating bridging group, sulfoxide, sulfone or carbonyl group using nitric acid in a solvent and free from other acids | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2003-08-19 | — | — | US | disclosed |
| CN-1426390-A | Process for producing bis (4-hydroxy-3-nitrophenyl) compound | NIPPON KAYAKU KK (JP) | 2003-06-25 | — | — | CN | disclosed |
| US-20030055288-A1 | Process for producting bis(4-hydroxy-3-nitrophenyl) compound | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2003-03-20 | — | — | US | disclosed |
| EP-1277727-A1 | PROCESS FOR PRODUCING BIS(4-HYDROXY-3-NITROPHENYL) COMPOUND | Nippon Kayaku Kabushiki Kaisha (JP) | 2003-01-22 | — | — | EP | disclosed |
| US-5977413-A | Method for producing bis(3-amino-4-hydroxyphenyl) compounds | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 1999-11-02 | — | — | US | disclosed |
| EP-0895985-A2 | Method for producing bis(3-amino-4-hydroxyphenyl) compounds | Nippon Kayaku Kabushiki Kaisha (JP) | 1999-02-10 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055288-A1 | Process for producting bis(4-hydroxy-3-nitrophenyl) compound | NOS3, NOS2, NOS1 | SMN1; SMN2 979/4885ALDH1A1 1215/4885MAPK1 2163/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.