SCHEMBL7108897

SCHEMBL7108897

Cc1ccc([S+]([O-])c2ccc(C)c(C)c2-c2ccccc2)c(-c2ccccc2)c1C

nearest known ligand 0.33

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ACHE P22303 2/20 0.33
AKT2 P31751 3/20 0.32
BRD4 O60885 2/20 0.32
CYP2A6 P11509 2/20 0.32
CYP1A2 P05177 2/20 0.32
CHEK1 O14757 1/20 0.32
BRD2 P25440 1/20 0.32
TSHR P16473 1/20 0.32
TDP2 O95551 1/20 0.32
NSD2 O96028 1/20 0.32
HSP90AA1 P07900 1/20 0.32
PAX8 Q06710 1/20 0.32
MAPT P10636 3/20 0.32
LMNA P02545 1/20 0.32
HTT P42858 1/20 0.32
PTGS1 P23219 1/20 0.32
PTGS2 P35354 1/20 0.32
AKT1 P31749 1/20 0.31
AKT3 Q9Y243 1/20 0.31
KMT2A Q03164 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4133965 0.78 FABP4 (0.39) ACHEAKT2BRD4CHEK1BRD2
SCHEMBL3684645 0.72 CYP1A2 (0.31) CYP2A6CYP1A2TSHRTDP2NSD2
SCHEMBL4473038 0.71 TDP2 (0.46) AKT2BRD4CYP2A6CYP1A2CHEK1
SCHEMBL982859 0.71 TRPA1 (0.44) CYP1A2HSP90AA1MAPTLMNAHTT
SCHEMBL4130368 0.71 BRD4 (0.42) BRD4CYP1A2TSHRHSP90AA1MAPT
SCHEMBL7112327 0.71 TNKS2 (0.39) BRD4CYP1A2HSP90AA1MAPTLMNA
SCHEMBL4447138 0.69 KMT2A (0.41) AKT2BRD4CYP2A6CYP1A2TSHR
SCHEMBL8337482 0.69 MAPT (0.36) ACHEAKT2BRD4CYP2A6CYP1A2
SCHEMBL30159162 0.69 FABP3 (0.41) AKT2BRD4CYP2A6CYP1A2CHEK1
SCHEMBL9808957 0.69 MAOA (0.35) AKT2BRD4MAPTLMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0794218-B1 Polycarbonate resin composition stabilized against radiation MITSUBISHI ENG PLASTICS CORP (JP) 2003-10-15 EP disclosed
EP-0753540-B1 Polycarbonate resin composition MITSUBISHI ENG PLASTICS CORP (JP) 2003-06-11 EP disclosed
US-6359028-B1 USED IN MEDICAL EQUIPMENT, DISCOLORATION INHIBITION MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2002-03-19 US disclosed
US-6040367-A EXCELLENT RESISTANCE TO AN IONIZING RADIATION, IN WHICH HETEROCYCLIC COMPOUND CONTAINING OXYMETHYLENE UNITS MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2000-03-21 US disclosed
US-5977206-A Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORP. (JP) 1999-11-02 US disclosed
US-5948838-A 0.01 TO 5 PARTS BY WEIGHT OF A COMPOUND CONTAINING OXYMETHYLENE UNIT MITSUBISHI ENGINEERING-PLASTICS CORP. (JP) 1999-09-07 US disclosed
EP-0794218-A2 Polycarbonate resin composition stabilized against radiation MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1997-09-10 EP disclosed
EP-0753540-A2 Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1997-01-15 EP disclosed