Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FTO | Q9C0B1 | 3/20 | 0.51 |
| ▸ | KDM6B | O15054 | 1/20 | 0.51 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.51 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.51 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.51 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.51 |
| ▸ | KDM3A | Q9Y4C1 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 2/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 3/20 | 0.42 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17914153 | 0.82 | TSHR (0.60) | TSHRMAPK1LMNAHPGDALDH1A1 | |
| SCHEMBL258224 | 0.81 | KDM6B (0.59) | FTOKDM6BALKBH2ALKBH3KDM5B | |
| SCHEMBL9870441 | 0.78 | FTO (0.56) | FTOKDM6BALKBH2ALKBH3KDM5B | |
| SCHEMBL10371115 | 0.77 | ALDH1A1 (0.50) | TSHRMAPK1HPGDHTTSMN1; SMN2 | |
| SCHEMBL6491004 | 0.77 | FTO (0.56) | FTOKDM6BALKBH2ALKBH3KDM5B | |
| SCHEMBL9868870 | 0.77 | FTO (0.53) | FTOKDM6BALKBH2ALKBH3KDM5B | |
| SCHEMBL18705678 | 0.76 | TSHR (0.53) | TSHRMAPK1USP2LMNAALDH1A1 | |
| SCHEMBL9870443 | 0.74 | FTO (0.52) | FTOKDM6BALKBH2ALKBH3KDM5B | |
| SCHEMBL7109226 | 0.73 | TSHR (0.50) | TSHRMAPK1LMNAHPGDALDH1A1 | |
| SCHEMBL6643903 | 0.72 | TSHR (0.52) | TSHRMAPK1LMNAHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030022266-A1 | Novel agents for replacement of NAD+/NADH system in enzymatic reactions | ENERGY, U.S. DEPARTMENT OF | 2003-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030022266-A1 | Novel agents for replacement of NAD+/NADH system in enzymatic reactions | NQO1, NADK, ME2 | FTO 1169/4885KDM6B 2121/4885ALKBH2 1682/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.