Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 9/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | CCR2 | P41597 | 2/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
| ▸ | GLP1R | P43220 | 1/20 | 0.40 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7109974 | 0.79 | RXFP1 (0.51) | RXFP1KMT2AMEN1TSHRCCR2 | |
| SCHEMBL5114074 | 0.78 | KMT2A (0.62) | RXFP1KMT2AMEN1TSHRCCR2 | |
| SCHEMBL7112858 | 0.75 | CCR2 (0.44) | CCR2ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL7154000 | 0.74 | L3MBTL1 (0.42) | RXFP1KMT2AMEN1TSHRCCR2 | |
| SCHEMBL32662692 | 0.73 | KMT2A (0.73) | RXFP1KMT2AMEN1TSHRGAA | |
| SCHEMBL5577029 | 0.72 | LIPC (0.61) | RXFP1KMT2AMEN1TSHRCCR2 | |
| SCHEMBL9389068 | 0.70 | KMT2A (0.60) | RXFP1KMT2AMEN1TSHRCCR2 | |
| SCHEMBL15530482 | 0.69 | RXFP1 (0.72) | RXFP1KMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL21394364 | 0.69 | KMT2A (0.59) | RXFP1KMT2AMEN1TSHRALDH1A1 | |
| SCHEMBL7168919 | 0.69 | RXFP1 (0.41) | RXFP1KMT2AMEN1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351924-A2 | DIAMINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | Bristol-Myers Squibb Pharma Company (US) | 2003-10-15 | — | — | EP | disclosed |
| WO-2002050019-A2 | DIAMINES AS MODULATORS OF CHEMOKINE RECEPTOR ACTIVITY | BRISTOL-MYERS SQUIBB PHARMA CO. (US) | 2002-06-27 | — | — | WO | disclosed |