Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.50 |
| ▸ | DCUN1D1 | Q96GG9 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 7/20 | 0.42 |
| ▸ | RAB9A | P51151 | 7/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 3/20 | 0.42 |
| ▸ | RELA | Q04206 | 3/20 | 0.42 |
| ▸ | PKM | P14618 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13238943 | 0.70 | SMN1; SMN2 (0.44) | NISCHDCUN1D1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL22162812 | 0.69 | CA12 (0.58) | NISCHDCUN1D1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL28077679 | 0.69 | LMNA (0.49) | SMN1; SMN2ALDH1A1LMNANPC1RAB9A | |
| SCHEMBL3569157 | 0.68 | NISCH (0.51) | NISCHDCUN1D1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL27489704 | 0.67 | SMN1; SMN2 (0.43) | SMN1; SMN2ALDH1A1LMNANPC1RAB9A | |
| SCHEMBL27368504 | 0.67 | LMNA (0.58) | NISCHSMN1; SMN2ALDH1A1KDM4EPOLB | |
| SCHEMBL2692579 | 0.66 | CA12 (0.59) | SMN1; SMN2ALDH1A1KDM4EPOLBLMNA | |
| SCHEMBL29629010 | 0.66 | PTGS2 (0.58) | SMN1; SMN2ALDH1A1KDM4EPOLBLMNA | |
| SCHEMBL26923012 | 0.66 | KDM4E (0.50) | NISCHDCUN1D1SMN1; SMN2ALDH1A1KDM4E | |
| SCHEMBL6923809 | 0.66 | CA12 (0.54) | NISCHSMN1; SMN2ALDH1A1KDM4EHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030083326-A1 | Dihydroxyphenyl derivatives for hepatoprotection and treatment of liver diseases | CHOONGWAE PHARM. CO., LTD. (KR) | 2003-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030083326-A1 | Dihydroxyphenyl derivatives for hepatoprotection and treatment of liver diseases | SLC10A1, SLC10A2, ABCB11 | NISCH 2150/4885DCUN1D1 2814/4885SMN1; SMN2 2470/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.