SCHEMBL7110240

SCHEMBL7110240

[c]1c[c]c(Oc2ccccc2)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 6/20 0.44
TSHR P16473 1/20 0.44
MAOA P21397 2/20 0.35
NR1H2 P55055 1/20 0.35
BAX Q07812 1/20 0.35
KMT2A Q03164 2/20 0.35
KDM4E B2RXH2 1/20 0.35
GLA P06280 1/20 0.35
MAPT P10636 1/20 0.35
MEN1 O00255 1/20 0.33
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33
NLRP3 Q96P20 1/20 0.33
MAOB P27338 2/20 0.32
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
ALDH1A1 P00352 1/20 0.32
HPGD P15428 1/20 0.32
CA4 P22748 1/20 0.31
GSTP1 P09211 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6680948 0.80 CA1 (0.42) LTA4HKMT2AKDM4EMAPTMEN1
Water SCHEMBL27530954 0.78 LTA4H (0.48) LTA4HTSHRMAOANR1H2BAX
SCHEMBL76698 0.76 LTA4H (0.50) LTA4HTSHRMAOANR1H2BAX
SCHEMBL28770243 0.74 LTA4H (0.48) LTA4HTSHRMAOANR1H2BAX
SCHEMBL27495028 0.73 LTA4H (0.42) LTA4HTSHRMAOANR1H2BAX
SCHEMBL8535180 0.72 LTA4H (0.52) LTA4HTSHRMAOANR1H2BAX
Water SCHEMBL28744175 0.72 LTA4H (0.67) LTA4HTSHRMAOANR1H2BAX
SCHEMBL49434 0.72 LTA4H (0.67) LTA4HTSHRMAOANR1H2BAX
SCHEMBL134369 0.71 LTA4H (0.44) LTA4HTSHRMAOANR1H2BAX
SCHEMBL6684055 0.71 MAOB (0.41) TSHRMAOAMAPTRAB9AMAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030065213-A1 Monohydric alcohol derived urethanes and their use in cosmetic formulations ALZO INTERNATIONAL, INC. 2003-04-03 US claimed
EP-1006984-A4 MONOHYDRIC ALCOHOL DERIVED URETHANES AND THEIR USE IN COSMETIC FORMULATIONS ALZO INC (US) 2002-01-16 EP claimed
EP-1006984-A1 MONOHYDRIC ALCOHOL DERIVED URETHANES AND THEIR USE IN COSMETIC FORMULATIONS Alzo, Inc. (US) 2000-06-14 EP claimed
US-5972324-A DIMERIC URETHANE COMPOUNDS DERIVED FROM MONOHYDRIC ALCOHOLS, GENERALLY FATTY ALCOHOLS, AND A DIISOCYANATE. ALZO, INCO. (US) 1999-10-26 US claimed
WO-1998032415-A1 MONOHYDRIC ALCOHOL DERIVED URETHANES AND THEIR USE IN COSMETIC FORMULATIONS ALZO, INC. (US) 1998-07-30 WO claimed
EP-0574507-B1 HIGHLY PROCESSABLE AROMATIC POLYAMIDE FIBERS, THEIR PRODUCTION AND USE DU PONT (US) 1994-08-10 EP claimed
EP-0416486-B1 High processable aromatic polyamide fibers, their production and use DU PONT (US) 1994-04-06 EP claimed
EP-0574507-A1 HIGHLY PROCESSABLE AROMATIC POLYAMIDE FIBERS, THEIR PRODUCTION AND USE. DU PONT (US) 1993-12-22 EP claimed
US-5270113-A Coated with lubricant, emulsifier, antistatic agent E. I. DU PONT DE NEMOURS AND COMPANY (US) 1993-12-14 US claimed
WO-1992015747-A1 HIGHLY PROCESSABLE AROMATIC POLYAMIDE FIBERS, THEIR PRODUCTION AND USE E.I. DU PONT DE NEMOURS AND COMPANY (US) 1992-09-17 WO claimed
JP-61293222-A None JP disclosed
EP-0707030-A1 Method and device for coating and/or mixing of polymeric materials DU PONT DE NEMOURS (DEUTSCHLAND) GMBH (DE) 1996-04-17 EP disclosed
JP-S61293222-A POLYAMIDE RESIN AND ITS PRODUCTION TOKYO INST OF TECHNOL 1986-12-24 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030065213-A1 Monohydric alcohol derived urethanes and their use in cosmetic formulations ADH1C, FFAR2, ADH1A LTA4H 1648/4885TSHR 2849/4885MAOA 482/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.