SCHEMBL134369

SCHEMBL134369

[c]1cc[c]c(Oc2ccccc2)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 7/20 0.44
TSHR P16473 1/20 0.44
NR1H2 P55055 1/20 0.35
BAX Q07812 1/20 0.35
MAOA P21397 1/20 0.35
KMT2A Q03164 2/20 0.35
KDM4E B2RXH2 1/20 0.35
GLA P06280 1/20 0.35
MAPT P10636 1/20 0.35
CA1 P00915 2/20 0.32
CA2 P00918 2/20 0.32
MAOB P27338 1/20 0.32
CA4 P22748 1/20 0.31
GSTP1 P09211 1/20 0.31
SOS1 Q07889 1/20 0.31
CA9 Q16790 1/20 0.31
PARP10 Q53GL7 1/20 0.31
PLA2G2A P14555 1/20 0.31
LMNA P02545 1/20 0.31
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4440599 0.80 LTA4H (0.55) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL707768 0.79
Water SCHEMBL27530954 0.78 LTA4H (0.48) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL7675046 0.76 KDM4E (0.36) MAOAKDM4EMAOBCA4LMNA
SCHEMBL76698 0.76 LTA4H (0.50) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL28770243 0.74 LTA4H (0.48) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL27495028 0.73 LTA4H (0.42) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL8535180 0.72 LTA4H (0.52) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL61732 0.71 LTA4H (0.57) LTA4HTSHRNR1H2BAXMAOA
SCHEMBL1535885 0.71 LTA4H (0.44) LTA4HTSHRNR1H2BAXMAOA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 357 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8481174-B2 Organic light-emitting compound of CIS-diarylethene derivatives, organic electroluminescent device using the same, and method of manufacturing the device SAMSUNG DISPLAY CO., LTD. (KR) 2013-07-09 US claimed
US-7887932-B2 Organosiloxane compound and organic light-emitting device comprising the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2011-02-15 US claimed
US-7879463-B2 low driving voltage, excellent efficiency and improved color purity; excellent electrical properties, thermal stability and photochemical stability SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2011-02-01 US claimed
US-7862907-B2 Dimethylenecyclohexane compound, method of preparing the same and organic light emitting device comprising the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2011-01-04 US claimed
US-20080036370-A1 Polymer having 1,8-naphtalimide group and organic light emitting device including the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2008-02-14 US claimed
US-20070276160-A1 Organic light-emitting compound of CIS-diarylethene derivatives, organic electroluminescent device using the same, and method of manufacturing the device SAMSUNG DISPLAY CO., LTD. (KR) 2007-11-29 US claimed
US-20070264526-A1 Dimethylenecyclohexane compound, method of preparing the same and organic light emitting device comprising the dimethylenecyclohexane compound SAMSUNG DISPLAY CO., LTD. (KR) 2007-11-15 US claimed
US-20070155981-A1 Arylene derivative and organic light emitting device manufactured using the same SAMSUNG DISPLAY CO., LTD. (KR) 2007-07-05 US claimed
US-20070048532-A1 Organosiloxane compound and organic light-emitting device comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2007-03-01 US claimed
US-20070026258-A1 Dimethylenecyclohexane compound, method of preparing the same and organic light emitting device comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2007-02-01 US claimed
WO-2001032616-A2 OXETANONE DERIVATIVES MULLINS JOHN JASON GENTRY (US) 2001-05-10 WO claimed
WO-2001032669-A1 OXETANONE DERIVATIVES MULLINS JOHN JASON GENTRY (US) 2001-05-10 WO claimed
EP-1000055-A1 SUBSTITUTED PYRAZOLES AS p38 KINASE INHIBITORS G.D. Searle & Co. (US) 2000-05-17 EP claimed
WO-1998052940-A1 SUBSTITUTED PYRAZOLES AS p38 KINASE INHIBITORS G.D. SEARLE AND CO. (US) 1998-11-26 WO claimed
EP-0688444-B1 POLYMERS EXHIBITING NONLINEAR OPTICAL PROPERTIES ALLIED SIGNAL INC (US) 1998-05-13 EP claimed
US-5670603-A POLYESTER,-ETHERS, AMIDES, URETHANES,-EPOXIDES,-IMIDES, AND CARBONATES BASED ON MONOMERS OF 9,9-BIS/SUBSTITUTED PHENYLFLUORENE COMPOUNDS HAVING ELECTRON WITHDRAWING AND DONATING GROUPS; HEAT RESISTANCE; THIN FILMS ALLIEDSIGNAL INC. (US) 1997-09-23 US claimed
EP-0688444-A1 POLYMERS EXHIBITING NONLINEAR OPTICAL PROPERTIES AlliedSignal Inc. (US) 1995-12-27 EP claimed
WO-1994020881-A1 POLYMERS EXHIBITING NONLINEAR OPTICAL PROPERTIES ALLIEDSIGNAL INC. (US) 1994-09-15 WO claimed
US-4383826-A DICARBAMATE COMPOUNDS USED FOR MAKING PROSTHETIC TEETH BLENDAX-WERKE R.SCHNEIDER GMBH & CO. (DE) 1983-05-17 US claimed
US-4097456-A Preparation of acetylene-substituted polyimide oligomers and polyimide polymers GULF RESEARCH & DEVELOPMENT COMPANY (US) 1978-06-27 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070048532-A1 Organosiloxane compound and organic light-emitting device comprising the same AOX1, PPOX, SQLE LTA4H 88/4885TSHR 3606/4885NR1H2 660/4885
US-20070276160-A1 Organic light-emitting compound of CIS-diarylethene derivatives, organic electroluminescent device using the same, and method of manufacturing the device LEF1, EML4, LAS1L LTA4H 52/4885TSHR 4511/4885NR1H2 351/4885
US-20070026258-A1 Dimethylenecyclohexane compound, method of preparing the same and organic light emitting device comprising the same CRY1, YTHDC1, EMC1 LTA4H 1152/4885TSHR 4258/4885NR1H2 97/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.