Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | NQO2 | P16083 | 1/20 | 0.32 |
| ▸ | MIF | P14174 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | BCL2 | P10415 | 1/20 | 0.31 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11247669 | 0.84 | ALDH1A1 (0.36) | ALDH1A1LMNAHPGDKDM4EMEN1 | |
| SCHEMBL14098088 | 0.80 | HPGD (0.35) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL14098089 | 0.79 | ALOX5 (0.36) | ALDH1A1ALOX5BCL2MCL1HSP90AA1 | |
| SCHEMBL14098257 | 0.77 | ALDH1A1 (0.39) | ALDH1A1LMNAHPGDMEN1KMT2A | |
| SCHEMBL14098103 | 0.76 | DRD2 (0.34) | DRD2 | |
| SCHEMBL14138476 | 0.76 | — | — | |
| SCHEMBL5103399 | 0.76 | HTR7 (0.38) | ALDH1A1LMNAMEN1KMT2AHTT | |
| SCHEMBL14138462 | 0.76 | DRD2 (0.35) | MIFCA2CA6DRD2 | |
| SCHEMBL4488551 | 0.75 | ALDH1A1 (0.50) | ALDH1A1LMNAHPGDKDM4EMEN1 | |
| SCHEMBL7111900 | 0.75 | ALDH1A1 (0.41) | ALDH1A1LMNAALOX5HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6207837-B1 | REACTING HALOGEN-SUBSTITUTED PHENYL DERIVATIVE WITH A DISULFIDE COMPOUND | NIPPON SUISAN KAISHA, LTD. (JP) | 2001-03-27 | — | — | US | claimed |
| EP-1026153-A1 | NOVEL PROCESS FOR PRODUCING DIBENZO[b,f]THIEPINE DERIVATIVES | Nippon Suisan Kaisha, Ltd. (JP) | 2000-08-09 | — | — | EP | claimed |
| US-7410997-B2 | Tricyclic fused heterocycle compounds, process for preparing the same and use thereof | NIPPON SULSAN KAISHA, LTD. (JP) | 2008-08-12 | — | — | US | disclosed |
| US-7410997-B2 | Tricyclic fused heterocycle compounds, process for preparing the same and use thereof | NIPPON SULSAN KAISHA, LTD. (JP) | 2008-08-12 | — | — | US | disclosed |
| US-20030065021-A1 | Tracheal smooth muscle relaxants | YAMASHITA SHINYA (JP) | 2003-04-03 | — | — | US | disclosed |
| US-6495592-B1 | DIBENZ(B,F)OXEPIN DERIVATIVES; ANTIASTHMATICS | NIPPON SUISAN KAISHA, LTD. (JP) | 2002-12-17 | — | — | US | disclosed |
| US-6207837-B1 | REACTING HALOGEN-SUBSTITUTED PHENYL DERIVATIVE WITH A DISULFIDE COMPOUND | NIPPON SUISAN KAISHA, LTD. (JP) | 2001-03-27 | — | — | US | disclosed |
| US-6180659-B1 | USING A DIBENZO(B,F)-(OXEPIN OR THIEPIN) COMPOUND | NIPPON SUISAN KAISHA, LTD. (JP) | 2001-01-30 | — | — | US | disclosed |
| EP-1026153-A1 | NOVEL PROCESS FOR PRODUCING DIBENZO[b,f]THIEPINE DERIVATIVES | Nippon Suisan Kaisha, Ltd. (JP) | 2000-08-09 | — | — | EP | disclosed |
| EP-0885610-A1 | TRACHEAL SMOOTH MUSCLE RELAXANT | NIPPON SUISAN KAISHA, LTD. (JP) | 1998-12-23 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030065021-A1 | Tracheal smooth muscle relaxants | MYLK, MUSK, CPT1B | ALDH1A1 2363/4885LMNA 1131/4885ALOX5 1061/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.