Known targets — ChEMBL curated mechanism
ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO
The experimentally established mechanism targets of Tetraethylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 known ✓ | O00255 | 4/20 | 0.92 |
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.92 |
| ▸ | TSHR | P16473 | 3/20 | 0.83 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.83 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | APP | P05067 | 5/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.32 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tetraethylene Glycol SCHEMBL27610211 | 1.00 | MEN1 (0.92) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| Tetraethylene Glycol SCHEMBL27473683 | 1.00 | MEN1 (0.92) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| Pentaethylene Glycol SCHEMBL31282309 | 1.00 | MEN1 (0.92) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| Triethylene Glycol SCHEMBL8939357 | 1.00 | MEN1 (0.92) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| Hexaethylene Glycol SCHEMBL6555741 | 1.00 | MEN1 (0.92) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| Triethylene Glycol SCHEMBL28055604 | 1.00 | MEN1 (0.92) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| Pentaethylene Glycol SCHEMBL28986980 | 1.00 | MEN1 (0.92) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| Triethylene Glycol SCHEMBL31493180 | 1.00 | MEN1 (0.92) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| Tetraethylene Glycol SCHEMBL9132284 | 1.00 | MEN1 (0.92) | MEN1KMT2ATSHRMAPK1ALDH1A1 | |
| Triethylene Glycol SCHEMBL28084498 | 0.96 | MEN1 (0.85) | MEN1KMT2ATSHRMAPK1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114413505-B | Composite absorption refrigerating system utilizing waste heat of fuel cell | 东南大学 | 2024-04-26 | — | — | CN | claimed |
| CN-107565097-A | Double collector sulphur positive poles and preparation method thereof and the application in lithium-sulfur cell | 厦门大学 | 2018-01-09 | — | — | CN | claimed |
| CN-114413505-B | Composite absorption refrigerating system utilizing waste heat of fuel cell | 东南大学 | 2024-04-26 | — | — | CN | disclosed |
| CN-113669940-B | Low-temperature waste heat enthalpy-increasing two-stage heat storage system | 华北电力大学（保定） | 2023-02-24 | — | — | CN | disclosed |
| CN-113669940-A | Low-temperature waste heat enthalpy-increasing two-stage heat storage system | 华北电力大学（保定） | 2021-11-19 | — | — | CN | disclosed |
| CN-110265651-A | A kind of battery with nonaqueous electrolyte and preparation method thereof | 厦门大学 | 2019-09-20 | — | — | CN | disclosed |
| US-9701854-B2 | Aqueous ink-jet inks containing random polyurethanes as binders | E I DU PONT DE NEMOURS AND COMPANY (US) | 2017-07-11 | — | — | US | disclosed |
| EP-2773700-B1 | AQUEOUS INK-JET INKS CONTAINING BRANCHED POLYURETHANES AS BINDERS | DU PONT (US) | 2017-06-21 | — | — | EP | disclosed |
| US-9475958-B2 | Aqueous ink-jet inks containing branched polyurethanes as binders | E I DU PONT DE NEMOURS AND COMPANY (US) | 2016-10-25 | — | — | US | disclosed |
| US-9441124-B2 | Aqueous ink-jet inks containing alternating polyurethanes as binders | E I DU PONT DE NEMOURS AND COMPANY (US) | 2016-09-13 | — | — | US | disclosed |
| CN-103199247-B | Preparation method of composite positive material with multi-level conductive network of lithium ion battery | UNIV CENTRAL SOUTH | 2015-05-27 | — | — | CN | disclosed |
| WO-2002064530-A1 | SULFONE-SULFOXIDE COMPOSITIONS FOR ENHANCE AROMATIC EXTRACTION | GAYLORD CHEMICAL CORPORATION (US) | 2002-08-22 | — | — | WO | disclosed |
| US-6432183-B1 | SOLVENT DYES AND PYRAZOLINE DYES WITH NONIONIC SURFACTANTS | HEWLETT-PACKARD COMPANY | 2002-08-13 | — | — | US | disclosed |
| US-6350823-B1 | ETHYLENIC UNSATURATED POLYMER, POLYUREA, POLYURETHANEUREAS AND POLYTHIOCARBAMATEUREAS WITH POLYCARBONATES, POLYETHERS OR POLYESTERS AND ETHYLENE | 3M INNOVATIVE PROPERTIES COMPANY | 2002-02-26 | — | — | US | disclosed |
| EP-1149879-A2 | Microemulsion techniques for ink jet inks | Hewlett-Packard Company (US) | 2001-10-31 | — | — | EP | disclosed |
| EP-1119586-A1 | POLYFUNCTIONAL POLYMER | 3M Innovative Properties Company (US) | 2001-08-01 | — | — | EP | disclosed |
| EP-1119587-A1 | PAVEMENT MARKING COMPOSITION | 3M Innovative Properties Company (US) | 2001-08-01 | — | — | EP | disclosed |
| US-6107436-A | POLYUREA/POLYURETHANE/POLYTHIOUREA COPOLYMERS HAVING POLYCARBONATE, POLYETHER AND/OR POLYESTER SEGMENTS, ISOCYANATE-REACTIVE UNSATURATED COMPOUND SEGMENTS, AND ASPARTIC ESTER-POLYAMINE DERIVATIVE CHAIN EXTENDER SEGMENTS | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-08-22 | — | — | US | disclosed |
| WO-2000020481-A1 | PAVEMENT MARKING COMPOSITION | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-04-13 | — | — | WO | disclosed |
| WO-2000020482-A1 | POLYFUNCTIONAL POLYMER | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2000-04-13 | — | — | WO | disclosed |