Triethylene Glycol

Triethylene Glycol

SCHEMBL8939357

O.OCCOCCOCCO

nearest known ligand 0.92

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

ABCC9ABL1ACEACHEACVR1ADORA1ADORA2AADORA2BADORA3ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3AGTR1ALOX5ATP4AATP4BBCRBTKCACNA1ACACNA1BCACNA1CCACNA1DCACNA1ECACNA1FCACNA1GCACNA1HCACNA1ICACNA1SCACNA2D1CACNA2D2CACNA2D3CACNA2D4CACNB1CACNB2CACNB3CACNB4CACNG1CACNG2CACNG3CACNG4CACNG5CACNG6CACNG7CACNG8CALCRLCFBCHRM1CHRM2CHRM3CHRM4CHRM5CHRNA1CHRNB1CHRNDCHRNECHRNGCRBNCUL4ACXCR1CXCR2DDB1DDCDHFRDPP4DRD2DRD3DRD4EGFRERBB2ERBB4ESR1ESR2FDPSFKBP1AFLT1FLT3FLT4GARTGHSRGRIA1GRIA2GRIA3GRIA4GRIK1GRIK2GRIK3GRIK4GRIK5GRIN2AGSK3AGSK3BHDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR1AHTR1BHTR1DHTR1EHTR1FHTR2AHTR2BHTR2CHTR3AHTR3BHTR3CHTR3DHTR3EHTR4HTR5AHTR6HTR7IDH1IDH2IMPA1ITGA2BITGB3JAK1JAK2JAK3KCNJ11KCNK3KCNK9KDRKITMEN1METMMP1MMP13MMP7MMP8NANOD2NS5bODC1OPG057OPRD1OPRK1OPRM1PPARP1PARP2PDE3APDE3BPDE4APDE4BPDE4CPDE4DPDGFRBPIK3CAPIK3CBPIK3CDPIK3CGPIK3R1PIK3R2PIK3R3PIK3R5PKLRPPARDPPATPTGS1PTGS2RBX1ROCK1ROCK2RRM1RRM2RRM2BSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASCNN1ASCNN1BSCNN1GSIGMAR1SLC10A2SLC5A2SLC6A2SLC6A3SLC6A4SLC9A3SYKTACR1THRATHRBTOP1TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYK2TYMSVDRampCblablaT-3blaT-4blaT-5blaT-6blaUOE-1dacAdacBdacCfolAfolPftsIgyrAgyrBileSmecAmrcAmrcBmrdAparCparEpbp2pbp4pbpApbpFrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmG3rpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUthyAykgMykgO

The experimentally established mechanism targets of Triethylene Glycol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
MEN1 known ✓ O00255 4/20 0.92
THRB known ✓ P10828 1/20 0.52
KMT2A Q03164 4/20 0.92
TSHR P16473 3/20 0.83
MAPK1 P28482 2/20 0.83
ALDH1A1 P00352 2/20 0.53
HTT P42858 1/20 0.52
MAPT P10636 1/20 0.52
APP P05067 5/20 0.35
USP2 O75604 1/20 0.32
LMNA P02545 1/20 0.32
CYP3A4 P08684 1/20 0.32
CASP1 P29466 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
SLCO1B3 Q9NPD5 1/20 0.32
SLCO1B1 Q9Y6L6 1/20 0.32
L3MBTL1 Q9Y468 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tetraethylene Glycol SCHEMBL27610211 1.00 MEN1 (0.92) MEN1KMT2ATSHRMAPK1ALDH1A1
Tetraethylene Glycol SCHEMBL7110780 1.00 MEN1 (0.92) MEN1KMT2ATSHRMAPK1ALDH1A1
Tetraethylene Glycol SCHEMBL27473683 1.00 MEN1 (0.92) MEN1KMT2ATSHRMAPK1ALDH1A1
Pentaethylene Glycol SCHEMBL31282309 1.00 MEN1 (0.92) MEN1KMT2ATSHRMAPK1ALDH1A1
Hexaethylene Glycol SCHEMBL6555741 1.00 MEN1 (0.92) MEN1KMT2ATSHRMAPK1ALDH1A1
Triethylene Glycol SCHEMBL28055604 1.00 MEN1 (0.92) MEN1KMT2ATSHRMAPK1ALDH1A1
Pentaethylene Glycol SCHEMBL28986980 1.00 MEN1 (0.92) MEN1KMT2ATSHRMAPK1ALDH1A1
Triethylene Glycol SCHEMBL31493180 1.00 MEN1 (0.92) MEN1KMT2ATSHRMAPK1ALDH1A1
Tetraethylene Glycol SCHEMBL9132284 1.00 MEN1 (0.92) MEN1KMT2ATSHRMAPK1ALDH1A1
Triethylene Glycol SCHEMBL28084498 0.96 MEN1 (0.85) MEN1KMT2ATSHRMAPK1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119196540-A Natural gas comprehensive conveying device 大连德泰港华燃气股份有限公司 2024-12-27 CN claimed
CN-115795378-A Fault positioning method for natural gas triethylene glycol dehydration system 中国石油天然气股份有限公司 2023-03-14 CN claimed
EP-3894419-A1 LITHIUM ALKYL ALUMINATES AS ALKYL TRANSFER REAGENTS UMICORE AG & Co. KG (DE) 2021-10-20 EP claimed
WO-2020120148-A1 LITHIUM ALKYL ALUMINATES AS ALKYL TRANSFER REAGENTS UMICORE AG. & CO. KG. (DE) 2020-06-18 WO claimed
CN-109486013-A A kind of polypropylene direct injection molding efficient enhanced halogen-free flameproof functional agglomerate and preparation method thereof 江苏万纳普新材料科技有限公司 2019-03-19 CN claimed
CN-106283656-A The postfinishing process of jacquard knitting fabric 常熟市大正纺织制版有限公司 2017-01-04 CN claimed
EP-0653763-A1 Ultraviolet hardenable, solventless conductive polymeric material SOPHIA SYSTEMS Co., Ltd. (JP) 1995-05-17 EP claimed
EP-4543313-A1 SYSTEMS AND METHODS FOR TUNING ABSORPTION PATHWAYS IN BIOABSORBABLE MATERIALS Cilag GmbH International (CH) 2025-04-30 EP disclosed
US-20240423620-A1 COMPRESSIBLE SURGICAL ADJUNCTS, CARTRIDGES, AND CARTRIDGE ASSEMBLIES AND METHODS OF MAKING SURGICAL ADJUNCTS CILAG GMBH INTERNATIONAL (CH) 2024-12-26 US disclosed
US-20240423613-A1 SYSTEMS AND METHODS FOR TUNING ABSORPTION PATHWAYS IN BIOABSORBABLE MATERIALS CILAG GMBH INTERNATIONAL (CH) 2024-12-26 US disclosed
WO-2024261658-A1 SYSTEMS AND METHODS FOR TUNING ABSORPTION PATHWAYS IN BIOABSORBABLE MATERIALS CILAG GMBH INTERNATIONAL (CH) 2024-12-26 WO disclosed
CN-115947752-B Phosphate ionic liquid, preparation method thereof and application of phosphate ionic liquid as basic lubricating liquid additive 烟台先进材料与绿色制造山东省实验室 2024-03-08 CN disclosed
CN-115850724-B Pretreatment method for retaining synchronous separation of lignin from carbohydrate in lignocellulose biomass 中国科学院广州能源研究所 2024-02-06 CN disclosed
CN-1315225-C Modified polyvinyl acetal resin SEKISUI CHEMICAL CO LTD (JP) 2007-05-09 CN disclosed
CN-1191122-C Waterlike talc solid catalyst for production of triethyl glycol monoethers DALIAN CHEMICAL PHYSICS INST (CN) 2005-03-02 CN disclosed
CN-1555590-A Modified polyvinyl acetal resin ��Ԩ��ѧ��ҵ��ʽ���� 2004-12-15 CN disclosed
CN-1275442-A Waterlike talc solid catalyst for production of triethyl glycol monoethers DALIAN CHEMICAL PHYSICS INST (CN) 2000-12-06 CN disclosed
CN-1165823-A Polymerizable diketopyrrolopyrroles and polymers prepared therewith CIBA GEIGY AG (CH) 1997-11-26 CN disclosed
US-5514729-A CONDUCTIVE POLYEPOXIDE FOR TRACES (WIRES) ON CIRCUIT BOARD SOPHIA SYSTEMS CO., LTD. (JP) 1996-05-07 US disclosed
EP-0653763-A1 Ultraviolet hardenable, solventless conductive polymeric material SOPHIA SYSTEMS Co., Ltd. (JP) 1995-05-17 EP disclosed