Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 8/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | CLK4 | Q9HAZ1 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 6/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.33 |
| ▸ | TRPM8 | Q7Z2W7 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7447549 | 0.88 | MAPT (0.43) | ALDH1A1CYP1A2CYP2C19MAPTNPSR1 | |
| SCHEMBL7107250 | 0.80 | RECQL (0.40) | ALDH1A1CYP1A2CYP2C19MAPTNPSR1 | |
| SCHEMBL7111035 | 0.79 | BRD4 (0.37) | ALDH1A1CYP1A2CYP2C19MAPT | |
| SCHEMBL7110679 | 0.79 | PDPK1 (0.38) | ALDH1A1CYP1A2CYP2C19RECQL | |
| SCHEMBL9218409 | 0.75 | ALDH1A1 (0.45) | ALDH1A1CYP1A2CYP2C19MAPTCYP2C9 | |
| SCHEMBL638668 | 0.75 | ALDH1A1 (0.45) | ALDH1A1CYP1A2CYP2C19MAPTL3MBTL1 | |
| SCHEMBL637848 | 0.73 | ALDH1A1 (0.44) | ALDH1A1CYP1A2CYP2C19MAPTLMNA | |
| SCHEMBL7449092 | 0.69 | ALDH1A1 (0.37) | ALDH1A1CYP1A2CYP2C19MAPTNPSR1 | |
| SCHEMBL7018481 | 0.67 | RAB9A (0.39) | ALDH1A1CYP1A2CYP2C19MAPTLMNA | |
| SCHEMBL23674777 | 0.66 | ALDH1A1 (0.47) | ALDH1A1CYP1A2CYP2C19MAPTCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030008901-A1 | Hydroxy pipecolate hydroxamic acid derivatives | MCCLURE KIM F (US) | 2003-01-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030008901-A1 | Hydroxy pipecolate hydroxamic acid derivatives | MMP1, MMP10, MMP3 | ALDH1A1 2265/4885CYP1A2 3206/4885CYP2C19 3639/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.