SCHEMBL7112137

SCHEMBL7112137

Cc1ccc(S(=O)(=O)c2ccc(C)c(C)c2-c2ccccc2)c(-c2ccccc2)c1C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP2 O95551 1/20 0.41
NSD2 O96028 1/20 0.41
HSP90AA1 P07900 1/20 0.41
PAX8 Q06710 1/20 0.41
AKT1 P31749 1/20 0.37
AKT2 P31751 1/20 0.37
AKT3 Q9Y243 1/20 0.37
MAPT P10636 2/20 0.37
LMNA P02545 1/20 0.37
HTT P42858 1/20 0.37
ALDH1A1 P00352 4/20 0.36
POLB P06746 2/20 0.36
SMN1; SMN2 Q16637 1/20 0.36
HTR6 P50406 1/20 0.36
KDM4E B2RXH2 2/20 0.36
CYP3A4 P08684 1/20 0.36
CYP2C9 P11712 1/20 0.36
MAOB P27338 1/20 0.36
GAA P10253 2/20 0.34
HPGD P15428 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7949512 0.87 TDP2 (0.39) TDP2NSD2HSP90AA1PAX8AKT1
SCHEMBL28736762 0.85 MYC (0.39) TDP2NSD2HSP90AA1PAX8AKT1
SCHEMBL5697810 0.81 SENP1 (0.47) TDP2NSD2HSP90AA1PAX8MAPT
SCHEMBL28543837 0.81 LMNA (0.39) MAPTLMNAHTTALDH1A1POLB
SCHEMBL4142033 0.78 CASP1 (0.49) MAPTLMNAHTTALDH1A1POLB
Biphenyl SCHEMBL11199366 0.74 KMT2A (0.49) MAPTLMNAALDH1A1POLBSMN1; SMN2
Hydrochloric Acid SCHEMBL5808148 0.74 MAOB (0.47) LMNAALDH1A1KDM4ECYP3A4CYP2C9
SCHEMBL28134095 0.73 MAOB (0.49) LMNAALDH1A1CYP3A4CYP2C9MAOB
SCHEMBL11777280 0.73 CYP2A6 (0.46) TDP2NSD2HSP90AA1PAX8MAPT
SCHEMBL8654400 0.72 ALDH1A1 (0.47) TDP2NSD2HSP90AA1PAX8MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0794218-B1 Polycarbonate resin composition stabilized against radiation MITSUBISHI ENG PLASTICS CORP (JP) 2003-10-15 EP disclosed
EP-0753540-B1 Polycarbonate resin composition MITSUBISHI ENG PLASTICS CORP (JP) 2003-06-11 EP disclosed
US-6359028-B1 USED IN MEDICAL EQUIPMENT, DISCOLORATION INHIBITION MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2002-03-19 US disclosed
US-6040367-A EXCELLENT RESISTANCE TO AN IONIZING RADIATION, IN WHICH HETEROCYCLIC COMPOUND CONTAINING OXYMETHYLENE UNITS MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 2000-03-21 US disclosed
US-5977206-A Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORP. (JP) 1999-11-02 US disclosed
US-5948838-A 0.01 TO 5 PARTS BY WEIGHT OF A COMPOUND CONTAINING OXYMETHYLENE UNIT MITSUBISHI ENGINEERING-PLASTICS CORP. (JP) 1999-09-07 US disclosed
EP-0794218-A2 Polycarbonate resin composition stabilized against radiation MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1997-09-10 EP disclosed
EP-0753540-A2 Polycarbonate resin composition MITSUBISHI ENGINEERING-PLASTICS CORPORATION (JP) 1997-01-15 EP disclosed
US-3948788-A DIARYL SULFONES, HALOGEN-FREE AROMATIC COMPOUNDS MONSANTO COMPANY (US) 1976-04-06 US disclosed
US-3948787-A DIARYL SULFONES, CARBOXYLIC ESTERS MONSANTO COMPANY (US) 1976-04-06 US disclosed