Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 16/20 | 0.68 |
| ▸ | CA9 | Q16790 | 14/20 | 0.68 |
| ▸ | CA12 | O43570 | 12/20 | 0.68 |
| ▸ | CA1 | P00915 | 12/20 | 0.68 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.64 |
| ▸ | CA4 | P22748 | 2/20 | 0.62 |
| ▸ | CA13 | Q8N1Q1 | 2/20 | 0.54 |
| ▸ | USP2 | O75604 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | CA6 | P23280 | 1/20 | 0.54 |
| ▸ | CA5A | P35218 | 1/20 | 0.54 |
| ▸ | CA7 | P43166 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | AGO2 | Q9UKV8 | 1/20 | 0.54 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.54 |
| ▸ | TTK | P33981 | 2/20 | 0.52 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28032548 | 0.90 | CA2 (0.73) | CA2CA9CA12CA1CA14 | |
| SCHEMBL7117232 | 0.86 | CA2 (0.77) | CA2CA9CA12CA1CA14 | |
| SCHEMBL1926937 | 0.86 | CA2 (0.67) | CA2CA9CA12CA1CA14 | |
| SCHEMBL6850257 | 0.83 | MAOA (0.68) | CA2CA9CA12CA1CA6 | |
| SCHEMBL27990769 | 0.83 | MAOA (0.68) | CA2CA9CA12CA1TTK | |
| SCHEMBL14320650 | 0.83 | CA12 (0.51) | CA2CA9CA12CA1CA14 | |
| SCHEMBL2914549 | 0.83 | ALDH1A1 (0.63) | CA2CA9CA12CA1CA14 | |
| SCHEMBL6848937 | 0.83 | CA2 (0.68) | CA2CA9CA12CA1CA14 | |
| SCHEMBL7234406 | 0.79 | CA2 (0.58) | CA2CA9CA12CA1CA14 | |
| Trimethylammonium SCHEMBL27979850 | 0.79 | CA2 (0.58) | CA2CA9CA12CA1CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030135055-A1 | Aminosulfonylbiphenyl derivatives | MERCK PATENT GMBH (DE) | 2003-07-17 | — | — | US | claimed |
| US-20030135055-A1 | Aminosulfonylbiphenyl derivatives | MERCK PATENT GMBH (DE) | 2003-07-17 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030135055-A1 | Aminosulfonylbiphenyl derivatives | APOB, F12, SERPINB1 | CA2 3516/4885CA9 4234/4885CA12 4747/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.