Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.67 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | RECQL | P46063 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 6/20 | 0.57 |
| ▸ | RAB9A | P51151 | 3/20 | 0.57 |
| ▸ | HTT | P42858 | 2/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.53 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7763476 | 0.96 | SMN1; SMN2 (0.64) | SMN1; SMN2MEN1KMT2AHPGDRECQL | |
| SCHEMBL7119082 | 0.88 | RAB9A (0.59) | SMN1; SMN2MEN1KMT2AHPGDKDM4E | |
| SCHEMBL7761958 | 0.84 | MEN1 (0.56) | SMN1; SMN2MEN1KMT2AHPGDKDM4E | |
| SCHEMBL7113128 | 0.82 | TAS1R3 (0.64) | SMN1; SMN2MEN1KMT2AHPGDKDM4E | |
| SCHEMBL10943491 | 0.82 | HPGD (0.78) | SMN1; SMN2MEN1KMT2AHPGDRECQL | |
| SCHEMBL12173052 | 0.81 | KMT2A (0.67) | SMN1; SMN2MEN1KMT2AHPGDRECQL | |
| SCHEMBL7763495 | 0.80 | SMN1; SMN2 (0.49) | SMN1; SMN2MEN1KMT2AHPGDRECQL | |
| SCHEMBL7120573 | 0.79 | TP53 (0.55) | SMN1; SMN2HPGDKDM4EALDH1A1MAPT | |
| SCHEMBL14452073 | 0.77 | NPC1 (0.56) | SMN1; SMN2MEN1KMT2AHPGDRECQL | |
| SCHEMBL14095981 | 0.77 | MAPT (0.64) | SMN1; SMN2MEN1KMT2AHPGDRECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030212074-A1 | Phosphate transport inhibitors | SMITHKLINE BEECHAM CORPORATION | 2003-11-13 | — | — | US | claimed |
| US-20030212074-A1 | Phosphate transport inhibitors | SMITHKLINE BEECHAM CORPORATION | 2003-11-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030212074-A1 | Phosphate transport inhibitors | SLC34A2, SLC34A3, SLC34A1 | SMN1; SMN2 4632/4885MEN1 2716/4885KMT2A 3005/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.