Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
| ▸ | RRM1 | P23921 | 1/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | PTPN22 | Q9Y2R2 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.32 |
| ▸ | ERN1 | O75460 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7117361 | 0.93 | MEN1 (0.34) | KMT2AMEN1MAPTSOS1 | |
| SCHEMBL18196067 | 0.89 | ALDH1A1 (0.34) | CYP3A4 | |
| SCHEMBL8088137 | 0.87 | SOS1 (0.32) | KMT2AMEN1SOS1 | |
| SCHEMBL12023085 | 0.86 | MEN1 (0.50) | KMT2AMEN1MAPTESR1ESR2 | |
| SCHEMBL4004222 | 0.84 | PTPN22 (0.44) | KMT2AMEN1MAPTESR1ESR2 | |
| SCHEMBL6928512 | 0.84 | PTPN22 (0.44) | KMT2AMEN1MAPTESR1ESR2 | |
| SCHEMBL7118719 | 0.82 | — | — | |
| SCHEMBL7117357 | 0.81 | HSP90AA1 (0.41) | KMT2AMEN1MAPTESR1ESR2 | |
| SCHEMBL7117366 | 0.80 | — | — | |
| SCHEMBL994000 | 0.79 | TRPA1 (0.46) | KMT2AMEN1MAPTESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041077-B1 | Phosphine derivative and polymer thereof and transition metal complex comprising the same | TAKASAGO PERFUMERY CO LTD (JP) | 2003-11-05 | — | — | EP | disclosed |
| EP-0864577-B1 | Optically active phosphine derivative having at least two vinyl groups, polymer produced using the same as monomer and transition metal complexes of these | TAKASAGO PERFUMERY CO LTD (JP) | 2003-02-05 | — | — | EP | disclosed |
| EP-0877029-B1 | Optically active phosphine derivative having vinyl group, polymer produced using the same as monomer and transition metal complexes of these | TAKASAGO PERFUMERY CO LTD (JP) | 2002-12-11 | — | — | EP | disclosed |
| US-6465594-B1 | POLYMERIZING VINYL-SUBSTITUTED BIS(DIARYLPHOSPHINO) BINAPHTHALENE COMPOUNDS OR COMPLEX, ESPECIALLY WITH A STYRENE AND DIVINYLBENZENE; USED TO CATALYZE ASYMMETRIC HYDROGENATION TO PRODUCE AN OPTICALLY ACTIVE AMINO ACID COMPOUND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-10-15 | — | — | US | disclosed |
| US-6248848-B1 | Optically active phosphine derivative having at least two vinyl groups, polymer produced using the same as monomer, and transition metal complexes of these | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2001-06-19 | — | — | US | disclosed |
| US-6143834-A | Optically active phosphine derivative having at least two vinyl groups, polymer produced using the same as monomer, and transition metal complexes of these | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2000-11-07 | — | — | US | disclosed |
| EP-1041077-A2 | Phosphine derivative and polymer thereof and transition metal complex comprising the same | Takasago International Corporation (JP) | 2000-10-04 | — | — | EP | disclosed |
| US-6022936-A | Optically active phosphine derivative having vinyl group, polymer produced using the same as monomer, and transition metal complexes of these | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2000-02-08 | — | — | US | disclosed |
| EP-0877029-A2 | Optically active phosphine derivative having vinyl group, polymer produced using the same as monomer and transition metal complexes of these | Takasago International Corporation (JP) | 1998-11-11 | — | — | EP | disclosed |
| EP-0864577-A2 | Optically active phosphine derivative having at least two vinyl groups, polymer produced using the same as monomer and transition metal complexes of these | Takasago International Corporation (JP) | 1998-09-16 | — | — | EP | disclosed |