⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL38662081 | 0.87 | WDR5 (0.34) | — | |
| SCHEMBL2967460 | 0.87 | WDR5 (0.34) | — | |
| SCHEMBL29785251 | 0.87 | WDR5 (0.34) | — | |
| SCHEMBL7117361 | 0.87 | MEN1 (0.34) | — | |
| SCHEMBL18196067 | 0.83 | ALDH1A1 (0.34) | — | |
| SCHEMBL8088137 | 0.81 | SOS1 (0.32) | — | |
| SCHEMBL7115270 | 0.80 | KMT2A (0.40) | — | |
| SCHEMBL7521120 | 0.80 | GPR84 (0.32) | — | |
| SCHEMBL7118719 | 0.77 | — | — | |
| SCHEMBL17747337 | 0.75 | HKDC1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041077-B1 | Phosphine derivative and polymer thereof and transition metal complex comprising the same | TAKASAGO PERFUMERY CO LTD (JP) | 2003-11-05 | — | — | EP | disclosed |
| US-6465594-B1 | POLYMERIZING VINYL-SUBSTITUTED BIS(DIARYLPHOSPHINO) BINAPHTHALENE COMPOUNDS OR COMPLEX, ESPECIALLY WITH A STYRENE AND DIVINYLBENZENE; USED TO CATALYZE ASYMMETRIC HYDROGENATION TO PRODUCE AN OPTICALLY ACTIVE AMINO ACID COMPOUND | TAKASAGO INTERNATIONAL CORPORATION (JP) | 2002-10-15 | — | — | US | disclosed |
| JP-2000281691-A | PHOSPHINE DERIVATIVE HAVING VINYL GROUP, POLYMER COMPOSED OF THE SAME AS MONOMER, AND TRANSITION METAL COMPLEX THEREOF | TAKASAGO INTERNATL CORP | 2000-10-10 | — | — | JP | disclosed |
| EP-1041077-A2 | Phosphine derivative and polymer thereof and transition metal complex comprising the same | Takasago International Corporation (JP) | 2000-10-04 | — | — | EP | disclosed |