Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.51 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7008324 | 0.88 | ITGB3 (0.52) | — | |
| SCHEMBL8350094 | 0.81 | POLB (0.59) | GAAPOLBKMT2AMEN1ESR2 | |
| SCHEMBL8350533 | 0.79 | POLB (0.57) | GAAPOLBKMT2AMEN1ESR2 | |
| SCHEMBL8353674 | 0.77 | MAPT (0.61) | GAAPOLBKMT2AMEN1ESR2 | |
| SCHEMBL8358497 | 0.75 | GAA (0.56) | GAAPOLBKMT2AMEN1ESR2 | |
| SCHEMBL8350476 | 0.75 | ALDH1A1 (0.63) | GAAPOLBKMT2AMEN1ESR2 | |
| Acetic Acid SCHEMBL8508080 | 0.75 | MAPT (0.59) | GAAPOLBKMT2AMEN1ESR2 | |
| SCHEMBL8350048 | 0.75 | SMN1; SMN2 (0.59) | GAAPOLBKMT2AMEN1ESR2 | |
| SCHEMBL8353740 | 0.75 | ALDH1A1 (0.53) | GAAPOLBKMT2AMEN1ESR2 | |
| SCHEMBL8351239 | 0.75 | MAPK1 (0.63) | KMT2AMEN1LMNAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030055244-A1 | Pyridyl-containing spirocyclic compounds as inhibitors of fibrinogen-dependent platelet aggregation | MILLENNIUM PHARMACEUTICALS, INC. | 2003-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030055244-A1 | Pyridyl-containing spirocyclic compounds as inhibitors of fibrinogen-dependent platelet aggregation | PF4, PFKP, FGB | GAA 4196/4885POLB 3718/4885KMT2A 4716/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.