Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.51 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7119451 | 1.00 | ELANE (0.51) | ELANEMCOLN3L3MBTL1NPSR1ACHE | |
| SCHEMBL7118507 | 0.86 | MAPT (0.52) | ELANEL3MBTL1LMNAALDH1A1KMT2A | |
| SCHEMBL7118504 | 0.86 | MAPT (0.52) | ELANEL3MBTL1LMNAALDH1A1KMT2A | |
| SCHEMBL8205234 | 0.86 | KMT2A (0.56) | ELANELMNAGAAPOLBNPC1 | |
| SCHEMBL7153332 | 0.86 | L3MBTL1 (0.56) | ELANEL3MBTL1NPSR1ACHEGAA | |
| SCHEMBL7153336 | 0.86 | L3MBTL1 (0.56) | ELANEL3MBTL1NPSR1ACHEGAA | |
| SCHEMBL7128095 | 0.84 | HSD11B1 (0.52) | NPC1RAB9AALDH1A1PKMMMP2 | |
| SCHEMBL7128097 | 0.84 | HSD11B1 (0.52) | NPC1RAB9AALDH1A1PKMMMP2 | |
| SCHEMBL6845966 | 0.82 | ALDH1A1 (0.50) | MCOLN3L3MBTL1NPSR1ACHELMNA | |
| SCHEMBL12574213 | 0.82 | ALDH1A1 (0.50) | MCOLN3L3MBTL1NPSR1ACHELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030153771-A1 | Large scale synthesis of optically pure aziridines | LEXICON PHARMACEUTICALS, INC. | 2003-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030153771-A1 | Large scale synthesis of optically pure aziridines | QDPR, AZI2, NISCH | ELANE 4478/4885MCOLN3 4817/4885L3MBTL1 4877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.