Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
| ▸ | PKLR | P30613 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MMP1 | P03956 | 10/20 | 0.49 |
| ▸ | MMP3 | P08254 | 10/20 | 0.49 |
| ▸ | MMP7 | P09237 | 7/20 | 0.49 |
| ▸ | MMP9 | P14780 | 6/20 | 0.49 |
| ▸ | MMP2 | P08253 | 5/20 | 0.49 |
| ▸ | MMP13 | P45452 | 3/20 | 0.49 |
| ▸ | MMP8 | P22894 | 3/20 | 0.49 |
| ▸ | ADAM17 | P78536 | 2/20 | 0.49 |
| ▸ | MMP12 | P39900 | 1/20 | 0.49 |
| ▸ | MMP14 | P50281 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7128097 | 1.00 | HSD11B1 (0.52) | HSD11B1NPC1PKMPKLRRAB9A | |
| SCHEMBL7119448 | 0.84 | ELANE (0.51) | NPC1PKMRAB9AALDH1A1MMP2 | |
| SCHEMBL7119451 | 0.84 | ELANE (0.51) | NPC1PKMRAB9AALDH1A1MMP2 | |
| SCHEMBL7118507 | 0.82 | MAPT (0.52) | PKMALDH1A1CYP3A4CYP2C19MMP2 | |
| SCHEMBL7118504 | 0.82 | MAPT (0.52) | PKMALDH1A1CYP3A4CYP2C19MMP2 | |
| SCHEMBL7153336 | 0.82 | L3MBTL1 (0.56) | RAB9AALDH1A1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL7153332 | 0.82 | L3MBTL1 (0.56) | RAB9AALDH1A1CYP3A4CYP2D6CYP2C19 | |
| SCHEMBL7056093 | 0.81 | MMP1 (0.62) | MMP1MMP3MMP7MMP9MMP2 | |
| SCHEMBL7059059 | 0.81 | MMP1 (0.50) | HSD11B1MMP1MMP3MMP7MMP9 | |
| SCHEMBL18988595 | 0.79 | HSD11B1 (0.51) | HSD11B1NPC1PKMPKLRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030153771-A1 | Large scale synthesis of optically pure aziridines | LEXICON PHARMACEUTICALS, INC. | 2003-08-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030153771-A1 | Large scale synthesis of optically pure aziridines | QDPR, AZI2, NISCH | HSD11B1 1108/4885NPC1 2709/4885PKM 4399/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.