Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | POLB | P06746 | 2/20 | 0.63 |
| ▸ | MMP2 | P08253 | 7/20 | 0.55 |
| ▸ | MMP9 | P14780 | 5/20 | 0.55 |
| ▸ | BMP1 | P13497 | 5/20 | 0.54 |
| ▸ | MMP3 | P08254 | 6/20 | 0.53 |
| ▸ | MMP1 | P03956 | 4/20 | 0.53 |
| ▸ | MMP13 | P45452 | 4/20 | 0.53 |
| ▸ | PDE4A | P27815 | 1/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.51 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.51 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.50 |
| ▸ | HPN | P05981 | 1/20 | 0.50 |
| ▸ | MMP8 | P22894 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7124459 | 0.90 | ALDH1A1 (0.57) | ALDH1A1POLBMMP2MMP9MMP1 | |
| SCHEMBL7127817 | 0.88 | MMP2 (0.53) | ALDH1A1POLBMMP2MMP9PLAU | |
| SCHEMBL7127019 | 0.85 | PLAU (0.60) | ALDH1A1MMP2MMP9PLAUHPN | |
| SCHEMBL7124501 | 0.84 | PLAU (0.54) | ALDH1A1MMP2MMP9MMP3PLAU | |
| SCHEMBL7125293 | 0.84 | PLAU (0.59) | ALDH1A1POLBMMP2MMP9MMP1 | |
| SCHEMBL7118405 | 0.84 | MMP2 (0.50) | ALDH1A1MMP2MMP9MMP3MMP1 | |
| SCHEMBL7117861 | 0.79 | PSMB8 (0.54) | ALDH1A1MMP2MMP9MMP1PLAU | |
| SCHEMBL7127030 | 0.79 | PSMB8 (0.51) | ALDH1A1MMP2MMP9MMP3MMP1 | |
| SCHEMBL7126168 | 0.78 | MMP2 (0.49) | ALDH1A1POLBMMP2MMP9MMP1 | |
| SCHEMBL7118677 | 0.78 | MMP2 (0.49) | ALDH1A1MMP2MMP9BMP1PLAU |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6583318-B2 | Carrying out a four component condensation reaction between components consisting of a sulfonamide, an aldehyde or ketone, an isocyanide and a carboxylic acid, and one of such components being attached to a solid support | ADVANCED SYNTECH, LLC | 2003-06-24 | — | — | US | disclosed |
| US-20030013910-A1 | Method for synthesis of alpha-sulfonamido amide, carboxylic acid and hydroxamic acid derivatives | ADVANCED SYNTECH LLC | 2003-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013910-A1 | Method for synthesis of alpha-sulfonamido amide, carboxylic acid and hydroxamic acid derivatives | ASPH, COASY, HAAO | ALDH1A1 391/4885POLB 1804/4885MMP2 2100/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.