Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 7/20 | 0.53 |
| ▸ | MMP9 | P14780 | 6/20 | 0.53 |
| ▸ | PLAU | P00749 | 1/20 | 0.53 |
| ▸ | HPN | P05981 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | MMP7 | P09237 | 1/20 | 0.48 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.48 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.48 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.46 |
| ▸ | MMP8 | P22894 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | MMP14 | P50281 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7124459 | 0.93 | ALDH1A1 (0.57) | MMP2MMP9PLAUHPNALDH1A1 | |
| SCHEMBL7121669 | 0.88 | ALDH1A1 (0.63) | MMP2MMP9PLAUHPNALDH1A1 | |
| SCHEMBL7127019 | 0.88 | PLAU (0.60) | MMP2MMP9PLAUHPNALDH1A1 | |
| SCHEMBL7125293 | 0.87 | PLAU (0.59) | MMP2MMP9PLAUHPNALDH1A1 | |
| SCHEMBL7118405 | 0.87 | MMP2 (0.50) | MMP2MMP9PLAUHPNALDH1A1 | |
| SCHEMBL7124501 | 0.87 | PLAU (0.54) | MMP2MMP9PLAUHPNALDH1A1 | |
| SCHEMBL7117861 | 0.82 | PSMB8 (0.54) | MMP2MMP9PLAUHPNALDH1A1 | |
| SCHEMBL7127030 | 0.81 | PSMB8 (0.51) | MMP2MMP9PLAUHPNALDH1A1 | |
| SCHEMBL7126168 | 0.81 | MMP2 (0.49) | MMP2MMP9PLAUHPNALDH1A1 | |
| SCHEMBL7118677 | 0.80 | MMP2 (0.49) | MMP2MMP9PLAUHPNALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6583318-B2 | Carrying out a four component condensation reaction between components consisting of a sulfonamide, an aldehyde or ketone, an isocyanide and a carboxylic acid, and one of such components being attached to a solid support | ADVANCED SYNTECH, LLC | 2003-06-24 | — | — | US | disclosed |
| US-20030013910-A1 | Method for synthesis of alpha-sulfonamido amide, carboxylic acid and hydroxamic acid derivatives | ADVANCED SYNTECH LLC | 2003-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013910-A1 | Method for synthesis of alpha-sulfonamido amide, carboxylic acid and hydroxamic acid derivatives | ASPH, COASY, HAAO | MMP2 2100/4885MMP9 3170/4885PLAU 1115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.