Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB8 | P28062 | 8/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 7/20 | 0.51 |
| ▸ | PLAU | P00749 | 1/20 | 0.47 |
| ▸ | HPN | P05981 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.45 |
| ▸ | MMP2 | P08253 | 2/20 | 0.44 |
| ▸ | MMP9 | P14780 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP14 | P50281 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | TMPRSS6 | Q8IU80 | 2/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | MMP3 | P08254 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7117861 | 0.86 | PSMB8 (0.54) | PSMB8PSMB5PLAUHPNMMP2 | |
| SCHEMBL7124501 | 0.84 | PLAU (0.54) | PSMB8PSMB5PLAUHPNMMP2 | |
| SCHEMBL7127817 | 0.81 | MMP2 (0.53) | PSMB8PSMB5PLAUHPNMMP2 | |
| SCHEMBL7124459 | 0.81 | ALDH1A1 (0.57) | PSMB8PSMB5PLAUHPNMMP2 | |
| SCHEMBL7127019 | 0.81 | PLAU (0.60) | PSMB8PSMB5PLAUHPNMMP2 | |
| SCHEMBL7118677 | 0.79 | MMP2 (0.49) | PSMB8PSMB5PLAUHPNMMP2 | |
| SCHEMBL7121669 | 0.79 | ALDH1A1 (0.63) | PLAUHPNMMP2MMP9MMP1 | |
| SCHEMBL7118405 | 0.76 | MMP2 (0.50) | PSMB8PSMB5PLAUHPNMMP2 | |
| SCHEMBL7125293 | 0.76 | PLAU (0.59) | PSMB8PLAUHPNMMP2MMP9 | |
| SCHEMBL7126168 | 0.71 | MMP2 (0.49) | PLAUHPNCA2MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6583318-B2 | Carrying out a four component condensation reaction between components consisting of a sulfonamide, an aldehyde or ketone, an isocyanide and a carboxylic acid, and one of such components being attached to a solid support | ADVANCED SYNTECH, LLC | 2003-06-24 | — | — | US | disclosed |
| US-20030013910-A1 | Method for synthesis of alpha-sulfonamido amide, carboxylic acid and hydroxamic acid derivatives | ADVANCED SYNTECH LLC | 2003-01-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030013910-A1 | Method for synthesis of alpha-sulfonamido amide, carboxylic acid and hydroxamic acid derivatives | ASPH, COASY, HAAO | PSMB8 2820/4885PSMB5 3386/4885PLAU 1115/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.