SCHEMBL709831

SCHEMBL709831

c1ccc(-c2ccc(Nc3nccc(-c4ccc(-c5ccc(N(c6ccccc6)c6ccccc6)cc5)cc4)n3)cc2)cc1

nearest known ligand 0.59

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
IKBKB O14920 4/20 0.59
MAPK8 P45983 3/20 0.59
MAPK10 P53779 2/20 0.59
ABL1 P00519 1/20 0.58
EGFR P00533 1/20 0.58
PRKCA P17252 1/20 0.58
PRKCD Q05655 1/20 0.58
CAMK2D Q13557 5/20 0.58
JAK2 O60674 3/20 0.57
JAK3 P52333 1/20 0.57
PIK3CG P48736 4/20 0.54
GSK3B P49841 2/20 0.54
CAMKK2 Q96RR4 2/20 0.54
PIK3CA P42336 2/20 0.52
PIK3CB P42338 2/20 0.52
PLK1 P53350 1/20 0.51
HDAC1 Q13547 1/20 0.49
HDAC6 Q9UBN7 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL710850 0.96 CAMK2D (0.63) IKBKBMAPK8MAPK10ABL1EGFR
SCHEMBL710336 0.89 SYK (0.55) IKBKBMAPK8MAPK10CAMK2DJAK2
SCHEMBL7472770 0.84 ABL1 (0.67) IKBKBMAPK8MAPK10ABL1EGFR
SCHEMBL1593016 0.83 PRKCD (0.79) IKBKBMAPK8MAPK10ABL1EGFR
SCHEMBL13185630 0.79 IKBKB (0.60) IKBKBMAPK8MAPK10ABL1EGFR
SCHEMBL28651097 0.78 IKBKB (0.53) IKBKBMAPK8MAPK10ABL1EGFR
SCHEMBL710577 0.77 SREBF2 (0.38) IKBKBMAPK8MAPK10CAMK2DJAK2
SCHEMBL2180914 0.77 ALDH1A1 (0.50)
SCHEMBL13177396 0.77 ALDH1A1 (0.50)
SCHEMBL10001584 0.77 ALDH1A1 (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8124762-B2 Diphenyl amine derivatives having luminescence property KOREA INSTITUTE OF SCIENCE & TECHNOLOGY (KR) 2012-02-28 US disclosed
US-8124762-B2 Diphenyl amine derivatives having luminescence property KOREA INSTITUTE OF SCIENCE & TECHNOLOGY (KR) 2012-02-28 US disclosed
US-8124762-B2 Diphenyl amine derivatives having luminescence property KOREA INSTITUTE OF SCIENCE & TECHNOLOGY (KR) 2012-02-28 US disclosed
US-20100063281-A1 DIPHENYL AMINE DERIVATIVES HAVING LUMINESCENCE PROPERTY KOREA INSTITUTE OF SCIENCE & TECHNOLOGY (KR) 2010-03-11 US disclosed
US-20100063281-A1 DIPHENYL AMINE DERIVATIVES HAVING LUMINESCENCE PROPERTY KOREA INSTITUTE OF SCIENCE & TECHNOLOGY (KR) 2010-03-11 US disclosed
US-20100063281-A1 DIPHENYL AMINE DERIVATIVES HAVING LUMINESCENCE PROPERTY KOREA INSTITUTE OF SCIENCE & TECHNOLOGY (KR) 2010-03-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100063281-A1 DIPHENYL AMINE DERIVATIVES HAVING LUMINESCENCE PROPERTY TYR, PNMT, DDC IKBKB 4028/4885MAPK8 3732/4885MAPK10 2827/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.