SCHEMBL7124233

SCHEMBL7124233

COc1ccc2c(c1)N(C)c1ccccc1S2

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOA P21397 1/20 0.63
KDM1A O60341 1/20 0.56
SNCA P37840 4/20 0.56
L3MBTL1 Q9Y468 4/20 0.55
NOX1 Q9Y5S8 3/20 0.55
MAPT P10636 3/20 0.55
LMNA P02545 2/20 0.55
MAPK1 P28482 2/20 0.55
TDP1 Q9NUW8 1/20 0.55
ADRA2A P08913 2/20 0.53
DRD3 P35462 2/20 0.53
CYP1A2 P05177 2/20 0.53
CYP2D6 P10635 2/20 0.53
CYP3A4 P08684 1/20 0.53
CHRM2 P08172 1/20 0.53
HTR1A P08908 1/20 0.53
CHRM1 P11229 1/20 0.53
DRD1 P21728 1/20 0.53
TBXA2R P21731 1/20 0.53
PTGS1 P23219 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31297952 1.00 MAOA (0.63) MAOAKDM1ASNCAL3MBTL1NOX1
SCHEMBL7123151 0.90 SNCA (0.69) MAOAKDM1ASNCAL3MBTL1NOX1
SCHEMBL7389154 0.80 SNCA (0.81) MAOASNCAL3MBTL1NOX1MAPT
SCHEMBL29067128 0.80 KDM1A (0.67) KDM1AL3MBTL1MAPTLMNAMAPK1
SCHEMBL10990789 0.80 NOX1 (0.63) MAOAL3MBTL1NOX1MAPTLMNA
SCHEMBL4758571 0.80 MAOA (0.63) MAOASNCAL3MBTL1NOX1MAPT
SCHEMBL231247 0.80 MAOA (1.00) MAOAKDM1AL3MBTL1NOX1MAPT
SCHEMBL29377505 0.80 MAOA (1.00) MAOAKDM1AL3MBTL1NOX1MAPT
SCHEMBL25258222 0.80 LMNA (0.63) KDM1AL3MBTL1NOX1MAPTLMNA
SCHEMBL28580030 0.80 MAPK1 (0.50) KDM1AL3MBTL1NOX1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20020119136-A1 Antimicrobial peroxidase compositions NOVOZYMES A/S (DK) 2002-08-29 US claimed
JP-2000512267-A 2000-09-19 JP claimed
EP-0912097-A1 ANTIMICROBIAL PEROXIDASE COMPOSITIONS NOVO NORDISK A/S (DK) 1999-05-06 EP claimed
WO-1997042825-A1 ANTIMICROBIAL PEROXIDASE COMPOSITIONS NOVO NORDISK A/S (DK) 1997-11-20 WO claimed
US-6660503-B2 In aqueous solution NOVOZYMES A/S (DK) 2003-12-09 US disclosed
EP-0935692-B1 FABRIC TREATED WITH CELLULASE AND OXIDOREDUCTASE NOVOZYMES AS (DK) 2002-11-27 EP disclosed
US-20020119136-A1 Antimicrobial peroxidase compositions NOVOZYMES A/S (DK) 2002-08-29 US disclosed
EP-0912097-B1 ANTIMICROBIAL PEROXIDASE COMPOSITIONS NOVOZYMES AS (DK) 2002-08-07 EP disclosed
EP-0787230-B1 BLEACHING PROCESS COMPRISING USE OF A PHENOL OXIDIZING ENZYME, A HYDROGEN PEROXIDE SOURCE AND AN ENHANCING AGENT NOVOZYMES AS (DK) 2002-03-20 EP disclosed
US-6346401-B1 OXIDATION OF HYDROXY GROUP OF SUGAR MONOMER OF STARCH BY CONTACTING WITH PEROXIDASE, HYDROGEN PEROXIDE AND ENHANCING AGENT IN AQUEOUS MEDIUM; FORMS CARBONYL OR CARBOXYLATE GROUP NOVOZYMES A/S (DK) 2002-02-12 US disclosed
US-20010055794-A1 Modification of polysaccharides by means of a phenol oxidizing enzyme NOVOZYMES A/S (DK) 2001-12-27 US disclosed
EP-0946207-B1 A METHOD FOR ENZYMATIC TREATMENT OF BIOFILM NOVOZYMES AS (DK) 2001-10-24 EP disclosed
WO-1997043383-A1 DETERGENT COMPOSITIONS COMPRISING LACCASE ENZYME THE PROCTER & GAMBLE COMPANY (US) 1997-11-20 WO disclosed
WO-1997043381-A1 DETERGENT COMPOSITION COMPRISING A CELLULASE ENZYME AND A LACCASE ENZYME THE PROCTER & GAMBLE COMPANY (US) 1997-11-20 WO disclosed
WO-1997043384-A1 DETERGENTS WITH PROTEASE ENZYME AND LACCASE ENZYME THE PROCTER & GAMBLE COMPANY (US) 1997-11-20 WO disclosed
WO-1997043382-A1 DETERGENT COMPOSITION COMPRISING A LACCASE ENZYME AND A DYE TRANSFER INHIBITING POLYMER THE PROCTER & GAMBLE COMPANY (US) 1997-11-20 WO disclosed
WO-1997040229-A1 FABRIC TREATED WITH A CELLULASE AND A HYBRID ENZYME COMPRISING A PHENOL OXIDIZING ENZYME NOVO NORDISK A/S (DK) 1997-10-30 WO disclosed
WO-1997040127-A1 BLEACHING OF FABRIC WITH A HYBRID ENZYME CONTAINING A PHENOL OXIDIZING ENZYME FUSED TO A CELLULOSE BINDING DOMAIN NOVO NORDISK A/S (DK) 1997-10-30 WO disclosed
WO-1997025469-A1 TEXTILES BLEACHING/BRIGHTENING NOVO NORDISK A/S (DK) 1997-07-17 WO disclosed
WO-1996006930-A1 COPRINACEAE LACCASES NOVO NORDISK A/S (DK) 1996-03-07 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020119136-A1 Antimicrobial peroxidase compositions LPO, MPO, GPX4 MAOA 1245/4885KDM1A 2783/4885SNCA 3122/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.