Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.35 |
| ▸ | MGAM | O43451 | 3/20 | 0.35 |
| ▸ | SI | P14410 | 3/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 3/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.34 |
| ▸ | NSD3 | Q9BZ95 | 1/20 | 0.33 |
| ▸ | MDM4 | O15151 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.33 |
| ▸ | AKT1 | P31749 | 1/20 | 0.33 |
| ▸ | AKT2 | P31751 | 1/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6370851 | 0.88 | GAA (0.40) | GAAMGAMSIMGAM2HSD11B1 | |
| SCHEMBL4622519 | 0.85 | HSD11B1 (0.41) | HSD11B1NSD3PTGS2BCHEACHE | |
| SCHEMBL28919625 | 0.77 | NSD3 (0.37) | GAAMGAMSIMGAM2NSD3 | |
| SCHEMBL2689067 | 0.76 | HSD11B1 (0.54) | GAAHSD11B1TP53KDM4ELMNA | |
| SCHEMBL31467384 | 0.76 | HSD11B1 (0.54) | GAAHSD11B1TP53KDM4ELMNA | |
| SCHEMBL28919628 | 0.74 | KDM4E (0.49) | GAAMGAMSIMGAM2NSD3 | |
| SCHEMBL29732755 | 0.72 | HSD11B1 (0.49) | HSD11B1TP53PTGS2BCHEACHE | |
| SCHEMBL63728 | 0.72 | HSD11B1 (0.49) | HSD11B1TP53PTGS2BCHEACHE | |
| SCHEMBL18037949 | 0.72 | GUSB (0.40) | GAAMGAMSIMGAM2AKT1 | |
| SCHEMBL5201695 | 0.70 | LMNA (0.50) | GAAMGAMSIMGAM2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0828182-B1 | Storage-stable photoimageable compositions with improved leuco dye | DU PONT (US) | 2003-11-19 | — | — | EP | claimed |