SCHEMBL7123980

SCHEMBL7123980

OCC(O)COCC(COCC(O)CO)(COCC(O)CO)COCC(O)CO

nearest known ligand 0.43

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.43
LMNA P02545 4/20 0.40
ALDH1A1 P00352 1/20 0.40
THRB P10828 1/20 0.33
KDM4E B2RXH2 3/20 0.31
CYP1A2 P05177 2/20 0.31
AGTR1 P30556 1/20 0.31
DUSP3 P51452 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
AR P10275 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20646701 0.97 USP2 (0.42) USP2LMNAALDH1A1THRBKDM4E
SCHEMBL20637056 0.97 USP2 (0.42) USP2LMNAALDH1A1THRBKDM4E
SCHEMBL1860602 0.90 USP2 (0.41) USP2LMNAALDH1A1THRB
SCHEMBL6285648 0.90 USP2 (0.41) USP2LMNAALDH1A1THRB
SCHEMBL19057791 0.89 USP2 (0.41) USP2LMNAALDH1A1KDM4ECYP1A2
SCHEMBL20438573 0.89 USP2 (0.46) USP2LMNAALDH1A1KDM4ECYP1A2
SCHEMBL20637053 0.86 USP2 (0.38) USP2LMNAALDH1A1THRB
SCHEMBL10806924 0.86 USP2 (0.47) USP2LMNAALDH1A1THRBKDM4E
SCHEMBL10044393 0.83 USP2 (0.44) USP2LMNAALDH1A1THRBKDM4E
SCHEMBL6258089 0.83 USP2 (0.44) USP2LMNAALDH1A1THRBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11768436-B2 Protective film forming composition having a diol structure NISSAN CHEMICAL CORPORATION (JP) 2023-09-26 US disclosed
US-20230098089-A1 MULTI-ARM SINGLE MOLECULAR WEIGHT POLYETHYLENE GLYCOL ACTIVE DERIVATIVE AND APPLICATION THEREOF JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) 2023-03-30 US disclosed
US-11518728-B2 Multi-arm single molecular weight polyethylene glycol, active derivative thereof, and preparation and application thereof JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) 2022-12-06 US disclosed
US-10660969-B2 Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2020-05-26 US disclosed
US-20200131109-A1 MULTI-ARM SINGLE MOLECULAR WEIGHT POLYETHYLENE GLYCOL, ACTIVE DERIVATIVE THEREOF, AND PREPARATION AND APPLICATION THEREOF JENKEM TECHNOLOGY CO., LTD. (TIANJIN) (CN) 2020-04-30 US disclosed
US-10434182-B2 Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2019-10-08 US disclosed
US-20190016856-A1 MULTI-ARMED POLYETHYLENE GLYCOL AND ACTIVE DERIVATIVE THEREOF JENKEM TECHNOLOGY CO., LTD. (BEIJING) (CN) 2019-01-17 US disclosed
US-20190016856-A1 MULTI-ARMED POLYETHYLENE GLYCOL AND ACTIVE DERIVATIVE THEREOF JENKEM TECHNOLOGY CO., LTD. (BEIJING) (CN) 2019-01-17 US disclosed
US-20180214561-A1 EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2018-08-02 US disclosed
US-20180214561-A1 EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2018-08-02 US disclosed
JP-2003246835-A NOVEL MULTIFUNCTIONAL EPOXY COMPOUND NIPPON STEEL CHEM CO LTD 2003-09-05 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10434182-B2 Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof MRPL38, ALG8, MRPS18A USP2 2760/4885LMNA 4044/4885ALDH1A1 1103/4885
US-10660969-B2 Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof MRPL38, ALG8, COG8 USP2 2452/4885LMNA 3900/4885ALDH1A1 787/4885
US-20180214561-A1 EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF MRPL38, CXCL8, ALG8 USP2 3075/4885LMNA 3842/4885ALDH1A1 1061/4885
US-20200131109-A1 MULTI-ARM SINGLE MOLECULAR WEIGHT POLYETHYLENE GLYCOL, ACTIVE DERIVATIVE THEREOF, AND PREPARATION AND APPLICATION THEREOF VEGFA, MYD88, FCGR2A USP2 501/4885LMNA 2251/4885ALDH1A1 2056/4885
US-20190016856-A1 MULTI-ARMED POLYETHYLENE GLYCOL AND ACTIVE DERIVATIVE THEREOF COG2, PTGER2, MGLL USP2 212/4885LMNA 1399/4885ALDH1A1 1584/4885
US-20230098089-A1 MULTI-ARM SINGLE MOLECULAR WEIGHT POLYETHYLENE GLYCOL ACTIVE DERIVATIVE AND APPLICATION THEREOF FCGR2A, VEGFA, FCGR3B USP2 393/4885LMNA 2397/4885ALDH1A1 2320/4885
US-11518728-B2 Multi-arm single molecular weight polyethylene glycol, active derivative thereof, and preparation and application thereof VEGFA, MYD88, FCGR2A USP2 501/4885LMNA 2251/4885ALDH1A1 2056/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.