Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 7/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL233713 | 0.79 | RAB9A (1.00) | RAB9AKMT2ATDP1ALDH1A1L3MBTL1 | |
| SCHEMBL11920128 | 0.78 | RAB9A (0.63) | RAB9AKMT2ATDP1ALDH1A1L3MBTL1 | |
| SCHEMBL7118364 | 0.75 | RAB9A (0.47) | RAB9AKMT2ATDP1ALDH1A1L3MBTL1 | |
| SCHEMBL3922051 | 0.74 | HPGD (0.70) | RAB9AKMT2ATDP1ALDH1A1L3MBTL1 | |
| SCHEMBL3591703 | 0.74 | HPGD (0.74) | RAB9AKMT2ATDP1ALDH1A1L3MBTL1 | |
| SCHEMBL31000977 | 0.74 | HPGD (0.74) | RAB9AKMT2ATDP1ALDH1A1L3MBTL1 | |
| SCHEMBL4235445 | 0.72 | RAB9A (0.86) | RAB9AKMT2ATDP1ALDH1A1L3MBTL1 | |
| SCHEMBL1578469 | 0.70 | RAB9A (0.83) | RAB9AKMT2ATDP1ALDH1A1L3MBTL1 | |
| SCHEMBL3901418 | 0.69 | TBXAS1 (0.54) | RAB9ATBXAS1NPC1MAPTSMN1; SMN2 | |
| SCHEMBL7388461 | 0.69 | TBXAS1 (0.56) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030114448-A1 | Inhibitors of factor Xa | MILLENNIUM PHARMACEUTICALS, INC. | 2003-06-19 | — | — | US | disclosed |
| WO-2002096873-A1 | ISOINDOLE AND ISOQUINOLINE DERIVATIVES AS INHIBITORS OF FACTOR XA | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2002-12-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030114448-A1 | Inhibitors of factor Xa | SERPINC1, F11, TFPI | RAB9A 1523/4885KMT2A 3746/4885TDP1 1108/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.