SCHEMBL7125594

SCHEMBL7125594

CC(=O)OCCCCC(CCCCOCCO)c1ccc(C)cc1

nearest known ligand 0.36

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ADRB2 P07550 3/20 0.36
ADRB3 P13945 1/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
PLA2G2C Q5R387 1/20 0.34
ALDH1A1 P00352 2/20 0.33
TDP1 Q9NUW8 1/20 0.33
SLC6A3 Q01959 1/20 0.32
PTGS2 P35354 1/20 0.32
LMNA P02545 1/20 0.32
THRB P10828 1/20 0.32
HTT P42858 1/20 0.32
MAPT P10636 1/20 0.32
STAT3 P40763 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid Butyl Ester SCHEMBL7898896 0.80 ALDH1A1 (0.56) MEN1KMT2AALDH1A1TDP1PTGS2
SCHEMBL14926442 0.78 TSHR (0.37) MEN1KMT2AALDH1A1
P-Xylene SCHEMBL8770845 0.74 LMNA (0.48) MEN1KMT2AALDH1A1TDP1LMNA
Butoxyethanol SCHEMBL7130512 0.74 ALDH1A1 (0.55) MEN1KMT2APLA2G2CALDH1A1LMNA
SCHEMBL7238397 0.74 PTGS2 (0.42) MEN1KMT2APLA2G2CALDH1A1TDP1
SCHEMBL8750490 0.74 NR1I2 (0.43) ADRB2MEN1KMT2APLA2G2CALDH1A1
SCHEMBL20963870 0.73 ALDH1A1 (0.54) MEN1KMT2AALDH1A1LMNATHRB
SCHEMBL18018653 0.70 CHRNB2 (0.39) ALDH1A1TDP1PTGS2LMNA
Acetic Acid Pentyl Ester SCHEMBL7772491 0.70 ALDH1A1 (0.63) ALDH1A1TDP1LMNAMAPT
P-Xylene SCHEMBL7218654 0.69 ALDH1A1 (0.57) MEN1KMT2APLA2G2CALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030225192-A1 Mxitures of 2-(2-hydroxy-4(3-butoxy-2-hydroxypropyloxy)-phenyl )-4,6-bis(2,4-dimethylphenyl)-1,3,5-triazine and hindered amine light stabilizers, used for stabilization of curable polycarbonates BIRBAUM JEAN-LUC (CH) 2003-12-04 US disclosed
US-6608122-B1 O-Hydroxyphenyl-s-triazines in combination with sterically hindered amines of the polyalkylpiperidine type CIBA SPECIALTY CHEMICALS CORPORATION 2003-08-19 US disclosed
US-5736597-A USING O-HYDROXYPHENYL-S-TRIAZINE AND STERIC HINDERED AMINE OF THE POLYALKYLPIPERIDINE TYPE CIBA-GEIGY CORPORATION (US) 1998-04-07 US disclosed
EP-0434608-B1 Stabilized organic material CIBA GEIGY AG (CH) 1997-04-02 EP disclosed
EP-0337942-B1 Liquid substituted 2H-benzotriazole mixtures CIBA GEIGY AG (CH) 1994-07-06 EP disclosed
US-5106891-A Ultraviolet light absorbers CIBA-GEIGY CORPORATION (US) 1992-04-21 US disclosed
EP-0434608-A1 Stabilized organic material CIBA-GEIGY AG (CH) 1991-06-26 EP disclosed
US-4880859-A GROUP TRANSFER POLYMERIZATION, COATINGS CIBA-GEIGY CORPORATION (US) 1989-11-14 US disclosed
EP-0337942-A1 Liquid substituted 2H-benzotriazole mixtures CIBA-GEIGY AG (CH) 1989-10-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030225192-A1 Mxitures of 2-(2-hydroxy-4(3-butoxy-2-hydroxypropyloxy)-phenyl )-4,6-bis(2,4-dimethylphenyl)-1,3,5-triazine and hindered amine light stabilizers, used for stabilization of curable polycarbonates SIGMAR1, H1-2, H1-5 ADRB2 956/4885ADRB3 2517/4885MEN1 2690/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.