Sulfuric Acid

Sulfuric Acid

SCHEMBL7128216

Cc1cc(O)ccc1N.O=S(=O)(O)O

nearest known ligand 0.52

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

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

The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.52
CYP3A4 P08684 5/20 0.52
TDP1 Q9NUW8 3/20 0.52
THRB P10828 3/20 0.52
ALOX15 P16050 3/20 0.52
RECQL P46063 3/20 0.52
HIF1A Q16665 2/20 0.52
TSHR P16473 2/20 0.46
GAA P10253 3/20 0.42
HPGD P15428 2/20 0.42
CASP1 P29466 2/20 0.42
HSD17B10 Q99714 2/20 0.42
KDM4E B2RXH2 2/20 0.42
MAPT P10636 2/20 0.42
PKM P14618 2/20 0.42
MEN1 O00255 1/20 0.42
RAB9A P51151 1/20 0.42
KMT2A Q03164 1/20 0.42
CYTH2 Q99418 4/20 0.41
TP53 P04637 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL34069 0.89
SCHEMBL4870452 0.89 CYP3A4 (0.61) ALDH1A1CYP3A4TDP1THRBALOX15
SCHEMBL29357630 0.89
Hydrochloric Acid SCHEMBL4653710 0.87 CYP3A4 (0.59) ALDH1A1CYP3A4TDP1THRBALOX15
Methane SCHEMBL27914972 0.87 CYP3A4 (0.59) ALDH1A1CYP3A4TDP1THRBALOX15
Hydrochloric Acid SCHEMBL29836028 0.87 CYP3A4 (0.59) ALDH1A1CYP3A4TDP1THRBALOX15
SCHEMBL4732895 0.87 CYP3A4 (0.59) ALDH1A1CYP3A4TDP1THRBALOX15
Bromide SCHEMBL11087469 0.87 CYP3A4 (0.59) ALDH1A1CYP3A4TDP1THRBALOX15
Hydrochloric Acid SCHEMBL22061862 0.85 CYP3A4 (0.57) ALDH1A1CYP3A4TDP1THRBALOX15
Methoxymethane SCHEMBL14813462 0.83 CYP3A4 (0.55) ALDH1A1CYP3A4TDP1THRBALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3634365-B1 HAIR COLORING COMPOSITION WITH IMPROVED SALT TOLERANCE HENKEL AG & CO KGAA (DE) 2022-08-10 EP claimed
EP-3496818-B1 PROCESS FOR PREPARING HAIR DYE AGENTS HAVING UNILAMELLAR AND MULTILAMELLAR VESICLES HENKEL AG & CO KGAA (DE) 2021-01-20 EP claimed
US-10736827-B2 Hair dye agent having unilamellar and multilamellar vesicles HENKEL AG & CO. KGAA (DE) 2020-08-11 US claimed
US-20200170904-A1 HAIR COLORING COMPOSITION WITH IMPROVED SALT TOLERANCE HENKEL AG & CO. KGAA (DE) 2020-06-04 US claimed
EP-3634365-A1 HAIR COLORING COMPOSITION WITH IMPROVED SALT TOLERANCE Henkel AG & Co. KGaA (DE) 2020-04-15 EP claimed
EP-3496818-A1 HAIR DYE AGENT HAVING UNILAMELLAR AND MULTILAMELLAR VESICLES Henkel AG & Co. KGaA (DE) 2019-06-19 EP claimed
US-20190175459-A1 HAIR DYE AGENT HAVING UNILAMELLAR AND MULTILAMELLAR VESICLES HENKEL AG & CO. KGAA (DE) 2019-06-13 US claimed
JP-58079247-A None JP disclosed
EP-3634365-B1 HAIR COLORING COMPOSITION WITH IMPROVED SALT TOLERANCE HENKEL AG & CO KGAA (DE) 2022-08-10 EP disclosed
EP-3496818-B1 PROCESS FOR PREPARING HAIR DYE AGENTS HAVING UNILAMELLAR AND MULTILAMELLAR VESICLES HENKEL AG & CO KGAA (DE) 2021-01-20 EP disclosed
US-10736827-B2 Hair dye agent having unilamellar and multilamellar vesicles HENKEL AG & CO. KGAA (DE) 2020-08-11 US disclosed
US-10702459-B2 Hair dye having improved viscosity stability HENKEL AG & CO. KGAA (DE) 2020-07-07 US disclosed
US-20200170904-A1 HAIR COLORING COMPOSITION WITH IMPROVED SALT TOLERANCE HENKEL AG & CO. KGAA (DE) 2020-06-04 US disclosed
EP-0079056-A2 Heat-developable color photographic material FUJI PHOTO FILM CO., LTD. (JP) 1983-05-18 EP disclosed
JP-S5879247-A COLOR PHOTOSENSITIVE MATERIAL DEVELOPABLE BY HEATING FUJI PHOTO FILM CO LTD 1983-05-13 JP disclosed
EP-0067455-A1 Heat-developable color photographic materials FUJI PHOTO FILM CO., LTD. (JP) 1982-12-22 EP disclosed
US-4258129-A IMPROVE GREEN SHELF LIFE FUJI PHOTO FILM CO., LTD. (JP) 1981-03-24 US disclosed
US-4211839-A SILVER HALIDE AND ORGANIC SILVER SALT PREPARED IN AN IMINO COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1980-07-08 US disclosed
US-4188212-A BEZNOTRIAZOLE FUJI PHOTO FILM CO., LTD. (JP) 1980-02-12 US disclosed
US-4138265-A Antifoggants in certain photographic and photothermographic materials that include silver salts of 3-amino-1,2,4-mercaptotriazole EASTMAN KODAK COMPANY (US) 1979-02-06 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10736827-B2 Hair dye agent having unilamellar and multilamellar vesicles EXOSC10, ANXA5, ANXA4 ALDH1A1 579/4885CYP3A4 1936/4885TDP1 4032/4885
US-20200170904-A1 HAIR COLORING COMPOSITION WITH IMPROVED SALT TOLERANCE UGCG, ADH1C, ELOVL1 ALDH1A1 105/4885CYP3A4 2826/4885TDP1 4092/4885
US-10702459-B2 Hair dye having improved viscosity stability KRT18, S100B, SHH ALDH1A1 1415/4885CYP3A4 2756/4885TDP1 3636/4885
US-20190175459-A1 HAIR DYE AGENT HAVING UNILAMELLAR AND MULTILAMELLAR VESICLES EXOSC10, ANXA5, ANXA4 ALDH1A1 579/4885CYP3A4 1936/4885TDP1 4032/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.