Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10419319 | 0.80 | ALDH1A1 (0.42) | ALDH1A1TSHRMAPK1TP53CYP3A4 | |
| SCHEMBL28378578 | 0.78 | ALDH1A1 (0.43) | ALDH1A1TSHRMAPK1TP53CYP3A4 | |
| SCHEMBL8760952 | 0.77 | ALDH1A1 (0.38) | ALDH1A1TSHRTP53CYP3A4 | |
| SCHEMBL8017741 | 0.75 | ALDH1A1 (0.38) | ALDH1A1TSHRMAPK1 | |
| SCHEMBL21084068 | 0.75 | ALDH1A1 (0.46) | ALDH1A1TSHRMAPK1TP53CYP3A4 | |
| SCHEMBL2463533 | 0.74 | TSHR (0.50) | ALDH1A1TSHRMAPK1TP53CYP3A4 | |
| SCHEMBL10528000 | 0.73 | ALDH1A1 (0.41) | ALDH1A1TSHRMAPK1TP53CYP3A4 | |
| SCHEMBL28675396 | 0.73 | ALDH1A1 (0.41) | ALDH1A1TSHRMAPK1TP53CYP3A4 | |
| SCHEMBL28096193 | 0.73 | ALDH1A1 (0.41) | ALDH1A1TSHRMAPK1TP53CYP3A4 | |
| SCHEMBL4075776 | 0.73 | ALDH1A1 (0.43) | ALDH1A1TSHRMAPK1TP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5776376-A | BLEND OF EPOXY AND UNSATURATED ESTER MONOMERS | TOKUYAMA CORPORATION (JP) | 1998-07-07 | — | — | US | claimed |
| US-12609210-B2 | Curable composition and cured body of same | TOKUYAMA CORPORATION (JP) | 2026-04-21 | — | — | US | disclosed |
| US-12595408-B2 | Photochromic compound, naphthol derivative, curable composition, optical article, lens, and eyeglasses | TOKUYAMA CORPORATION (JP) | 2026-04-07 | — | — | US | disclosed |
| EP-4692072-A1 | PHOTOCHROMIC COMPOUND, PROPARGYL ALCOHOL COMPOUND, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND SPECTACLES | TOKUYAMA CORPORATION (JP) | 2026-02-11 | — | — | EP | disclosed |
| EP-4692071-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASS | TOKUYAMA CORPORATION (JP) | 2026-02-11 | — | — | EP | disclosed |
| US-20250355282-A1 | LAYERED BODY, OPTICAL ARTICLE, LENS, AND SPECTACLES | TOKUYAMA CORPORATION (JP) | 2025-11-20 | — | — | US | disclosed |
| US-12434265-B2 | Coating method | TOKUYAMA CORPORATION (JP) | 2025-10-07 | — | — | US | disclosed |
| EP-4560367-A1 | LAYERED BODY, OPTICAL ARTICLE, LENS, AND SPECTACLES | TOKUYAMA CORPORATION (JP) | 2025-05-28 | — | — | EP | disclosed |
| US-20250122163-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | TOKUYAMA CORPORATION (JP) | 2025-04-17 | — | — | US | disclosed |
| WO-2025070122-A1 | PHOTOCHROMIC COMPOSITION, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | 株式会社トクヤマ | 2025-04-03 | — | — | WO | disclosed |
| US-5879591-A | MIXING PHOTOCHROMIC SPIROOXAZINE COMPOUND, POLYFUNCTIONAL ACRYLATE CONTAINING COLOR-FORMING IMPURITIES, HEAT POLYMERIZATION INITIATOR, EPOXIDE COMPOUND TO REDUCE INITIAL COLORING OF CURED PRODUCT | TOKUYAMA CORPORATION (JP) | 1999-03-09 | — | — | US | disclosed |
| US-5808100-A | DURABILITY | TOKUYAMA CORPORATION (JP) | 1998-09-15 | — | — | US | disclosed |
| US-5776376-A | BLEND OF EPOXY AND UNSATURATED ESTER MONOMERS | TOKUYAMA CORPORATION (JP) | 1998-07-07 | — | — | US | disclosed |
| US-5708063-A | REVERSABLE COLOR COMPOUNDS | TOKUYAMA CORPORATION (JP) | 1998-01-13 | — | — | US | disclosed |
| EP-0778276-A1 | Photochromic chromene derivatives | TOKUYAMA CORPORATION (JP) | 1997-06-11 | — | — | EP | disclosed |
| US-5631382-A | PHOTOCHROMIC LENSES | TOKUYAMA CORPORATION (JP) | 1997-05-20 | — | — | US | disclosed |
| EP-0773273-A1 | PROCESS FOR THE PRODUCTION OF PHOTOCHROMIC PRODUCT OF CURING | TOKUYAMA CORPORATION (JP) | 1997-05-14 | — | — | EP | disclosed |
| EP-0773272-A1 | PHOTOCHROMIC CURABLE COMPOSITION | TOKUYAMA CORPORATION (JP) | 1997-05-14 | — | — | EP | disclosed |
| EP-0696582-A1 | Polycyclic spirophthalimide derivatives, process for their preparation and their use as fulgimides | TOKUYAMA CORPORATION (JP) | 1996-02-14 | — | — | EP | disclosed |
| EP-0629626-A2 | Cyclopropyl-substituted spiro-photochromic compounds | TOKUYAMA CORPORATION (JP) | 1994-12-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12609210-B2 | Curable composition and cured body of same | UACA, MMAB, SMCHD1 | ALDH1A1 2725/4885TSHR 960/4885MAPK1 2426/4885 |
| US-12595408-B2 | Photochromic compound, naphthol derivative, curable composition, optical article, lens, and eyeglasses | CRYAA, CRYZ, CRY2 | ALDH1A1 185/4885TSHR 2387/4885MAPK1 1443/4885 |
| US-20250122163-A1 | PHOTOCHROMIC COMPOUND, NAPHTHOL DERIVATIVE, CURABLE COMPOSITION, OPTICAL ARTICLE, LENS, AND EYEGLASSES | CCNE1, NAP1L1, CRYZ | ALDH1A1 1010/4885TSHR 2592/4885MAPK1 457/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.