Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP24A1 | Q07973 | 3/20 | 0.52 |
| ▸ | CYP27B1 | O15528 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.45 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | PRKACA | P17612 | 1/20 | 0.41 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.41 |
| ▸ | IRAK1 | P51617 | 1/20 | 0.41 |
| ▸ | PRKX | P51817 | 1/20 | 0.41 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.41 |
| ▸ | PRKG2 | Q13237 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | PRKG1 | Q13976 | 1/20 | 0.41 |
| ▸ | PKN2 | Q16513 | 1/20 | 0.41 |
| ▸ | HIPK4 | Q8NE63 | 1/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.41 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.41 |
| ▸ | CSNK1G1 | Q9HCP0 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2347291 | 0.96 | SMN1; SMN2 (0.49) | CYP24A1CYP27B1SMN1; SMN2CYP19A1 | |
| SCHEMBL10860461 | 0.73 | CYP19A1 (0.46) | CYP24A1CYP27B1CYP19A1 | |
| SCHEMBL1503385 | 0.68 | CYP24A1 (1.00) | CYP24A1CYP27B1 | |
| SCHEMBL8540395 | 0.68 | CYP24A1 (1.00) | CYP24A1CYP27B1 | |
| SCHEMBL1503388 | 0.68 | CYP24A1 (1.00) | CYP24A1CYP27B1 | |
| SCHEMBL6571604 | 0.68 | SMN1; SMN2 (0.84) | SMN1; SMN2CYP19A1NAMPT | |
| SCHEMBL27354750 | 0.68 | HIF1A (0.54) | CYP24A1CYP27B1SMN1; SMN2NAMPTMCHR1 | |
| SCHEMBL10852854 | 0.67 | SMN1; SMN2 (0.58) | CYP24A1CYP27B1SMN1; SMN2 | |
| SCHEMBL331966 | 0.67 | CYP19A1 (0.90) | SMN1; SMN2CYP19A1 | |
| SCHEMBL16712996 | 0.66 | ROCK2 (0.74) | SMN1; SMN2ROCK2PRKACARPS6KB1IRAK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003045381-A1 | AMINOALKYLIMIDAZOLE DERIVATIVES AND THEIR USE IN MEDICINE | MOLECULAR SKINCARE LIMITED (GB) | 2003-06-05 | — | — | WO | claimed |
| WO-2003045381-A1 | AMINOALKYLIMIDAZOLE DERIVATIVES AND THEIR USE IN MEDICINE | MOLECULAR SKINCARE LIMITED (GB) | 2003-06-05 | — | — | WO | disclosed |