Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCZ | Q05513 | 4/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | BRAF | P15056 | 2/20 | 0.39 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.36 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.36 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 2/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.35 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7127148 | 0.69 | ESD (0.49) | PRKCZKIF11 | |
| SCHEMBL7456837 | 0.68 | MAOB (0.73) | PRKCZKIF11MAOBMAOA | |
| SCHEMBL6294120 | 0.67 | MEN1 (0.42) | PRKCZNR3C2MAOBMAOA | |
| SCHEMBL7131258 | 0.65 | MAOA (0.48) | PRKCZMAOBMAOABCHEACHE | |
| SCHEMBL25274761 | 0.64 | KIF11 (0.53) | PRKCZKIF11MAOBMAOA | |
| SCHEMBL29808134 | 0.63 | HSD17B1 (0.62) | PIK3CAPIK3CBPIK3CGHSD17B1HSD17B2 | |
| SCHEMBL184352 | 0.63 | HSD17B1 (0.62) | PIK3CAPIK3CBPIK3CGHSD17B1HSD17B2 | |
| SCHEMBL29683459 | 0.63 | HSD17B1 (0.62) | PIK3CAPIK3CBPIK3CGHSD17B1HSD17B2 | |
| SCHEMBL7461031 | 0.63 | MAOB (0.73) | KIF11MAOBMAOA | |
| SCHEMBL2484955 | 0.62 | HSD17B1 (0.60) | PIK3CAPIK3CBPIK3CGHSD17B1HSD17B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030083351-A1 | Medicinal uses of dihydropyrazoles | THE PROCTER & GAMBLE COMPANY | 2003-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030083351-A1 | Medicinal uses of dihydropyrazoles | EPOR, VEGFA, TEK | PRKCZ 1874/4885KIF11 3846/4885BRAF 3011/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.