Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 4/20 | 0.52 |
| ▸ | SNCA | P37840 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | APP | P05067 | 3/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.46 |
| ▸ | TRIM33 | Q9UPN9 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | CTSL | P07711 | 2/20 | 0.40 |
| ▸ | CTSB | P07858 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3451810 | 1.00 | SNCA (0.53) | SNCAACHEMAPTAPPPTGS2 | |
| SCHEMBL14536918 | 0.98 | SNCA (0.54) | SNCAACHEMAPTAPPPTGS2 | |
| SCHEMBL10069282 | 0.86 | ACHE (0.68) | SNCAACHEMAPTAPPALDH1A1 | |
| SCHEMBL10069285 | 0.86 | ACHE (0.68) | SNCAACHEMAPTALDH1A1KDM4E | |
| Stilbazium SCHEMBL710325 | 0.84 | MAPT (0.44) | SNCAACHEMAPTAPPPTGS2 | |
| Stilbazium SCHEMBL710326 | 0.84 | MAPT (0.44) | SNCAACHEMAPTAPPPTGS2 | |
| Stilbazium SCHEMBL6446924 | 0.82 | MAPT (0.46) | SNCAACHEMAPTAPPPTGS2 | |
| Iodide SCHEMBL7644264 | 0.82 | RAB9A (0.55) | SNCAACHEMAPTAPPPTGS2 | |
| Stilbazium SCHEMBL636481 | 0.81 | SNCA (0.47) | SNCAACHEMAPTAPPPTGS2 | |
| Stilbazium SCHEMBL636482 | 0.81 | SNCA (0.47) | SNCAACHEMAPTAPPPTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-4742028-B2 | — | — | 2011-08-10 | — | — | JP | claimed |
| US-7820696-B2 | Compounds and methods for controlling fungi, bacteria and insects | MYCOSOL, INC. (US) | 2010-10-26 | — | — | US | claimed |
| US-20070213299-A1 | COMPOUNDS AND METHODS FOR CONTROLLING FUNGI, BACTERIA AND INSECTS | MYCOSOL, INC. | 2007-09-13 | — | — | US | claimed |
| US-7220761-B2 | Compounds and methods for controlling fungi, bacteria and insects | MYCOSOL, INC. (US) | 2007-05-22 | — | — | US | claimed |
| WO-2007056340-A2 | DISINFECTANT AND ANTISEPTIC PYRIDINIUM AND THIAZOLIUM COMPOUNDS AND METHODS OF USING THE SAME | MYCOSOL, INC. (US) | 2007-05-18 | — | — | WO | claimed |
| EP-1601652-A2 | PYRIDINIUM SALTS, COMPOUNDS AND METHODS OF USE | Mycosol, Inc. (US) | 2005-12-07 | — | — | EP | claimed |
| US-20040235898-A1 | Compounds and methods for controlling fungi, bacteria and insects | MYCOSOL, INC. | 2004-11-25 | — | — | US | claimed |
| WO-2004078136-A2 | PYRIDINIUM SALTS, COMPOUNDS AND METHODS OF USE | MYCOSOL, INC. (US) | 2004-09-16 | — | — | WO | claimed |
| US-8124626-B2 | Methods of treating inflammations and infections with pyridinium salts | MYCOSOL, INC. (US) | 2012-02-28 | — | — | US | disclosed |
| US-7820696-B2 | Compounds and methods for controlling fungi, bacteria and insects | MYCOSOL, INC. (US) | 2010-10-26 | — | — | US | disclosed |
| US-20100267716-A1 | METHODS OF TREATING INFLAMMATIONS AND INFECTIONS WITH PYRIDINIUM SALTS | KLEIN RICHARD B | 2010-10-21 | — | — | US | disclosed |
| US-7547444-B1 | Methods for controlling fungi and bacteria | MYCOSOL, INC. (US) | 2009-06-16 | — | — | US | disclosed |
| US-20090137639-A1 | METHODS FOR CONTROLLING FUNGI AND BACTERIA | MYCOSOL, INC. | 2009-05-28 | — | — | US | disclosed |
| EP-1601652-B1 | PYRIDINIUM SALTS, COMPOUNDS AND METHODS OF USE | MYCOSOL INC (US) | 2008-07-30 | — | — | EP | disclosed |
| WO-2008088917-A2 | METHODS OF USING PYRIDINIUM AND THIAZOLIUM COMPOUNDS AS REAGENTS, DIAGNOSTIC COMPOUNDS AND THERAPEUTIC AGENTS | MYCOSOL, INC. (US) | 2008-07-24 | — | — | WO | disclosed |
| US-20070213299-A1 | COMPOUNDS AND METHODS FOR CONTROLLING FUNGI, BACTERIA AND INSECTS | MYCOSOL, INC. | 2007-09-13 | — | — | US | disclosed |
| US-7220761-B2 | Compounds and methods for controlling fungi, bacteria and insects | MYCOSOL, INC. (US) | 2007-05-22 | — | — | US | disclosed |
| US-20040235898-A1 | Compounds and methods for controlling fungi, bacteria and insects | MYCOSOL, INC. | 2004-11-25 | — | — | US | disclosed |
| US-20040224984-A1 | Methods of treating inflammations and infections with pyridinium salts | MYCOSOL, INC. | 2004-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070213299-A1 | COMPOUNDS AND METHODS FOR CONTROLLING FUNGI, BACTERIA AND INSECTS | BLVRB, PNPO, PLPBP | ACHE 39/4885SNCA 2090/4885MAPT 1618/4885 |
| US-20090137639-A1 | METHODS FOR CONTROLLING FUNGI AND BACTERIA | PNPO, BLVRB, DPM1 | ACHE 289/4885SNCA 2194/4885MAPT 1062/4885 |
| US-20040235898-A1 | Compounds and methods for controlling fungi, bacteria and insects | BLVRB, PNPO, PLPBP | ACHE 39/4885SNCA 2090/4885MAPT 1618/4885 |
| US-20100267716-A1 | METHODS OF TREATING INFLAMMATIONS AND INFECTIONS WITH PYRIDINIUM SALTS | PNPO, PLPBP, TPMT | ACHE 226/4885SNCA 2613/4885MAPT 2157/4885 |
| US-20040224984-A1 | Methods of treating inflammations and infections with pyridinium salts | PNPO, PLPBP, TPMT | ACHE 226/4885SNCA 2613/4885MAPT 2157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.