Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S100B | P04271 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27522744 | 0.89 | MAPT (0.43) | S100BS1PR1MAPT | |
| SCHEMBL1007816 | 0.83 | MAPT (0.47) | S100BS1PR1MAPT | |
| SCHEMBL21209088 | 0.79 | S100B (0.62) | S100BS1PR1MAPT | |
| SCHEMBL7763414 | 0.76 | ALDH1A1 (0.43) | S100BS1PR1MAPT | |
| SCHEMBL10066014 | 0.74 | ALDH1A1 (0.42) | S100BS1PR1MAPT | |
| SCHEMBL9464475 | 0.73 | NPSR1 (0.44) | MAPT | |
| SCHEMBL1010343 | 0.70 | — | — | |
| SCHEMBL29554953 | 0.70 | — | — | |
| SCHEMBL29370268 | 0.70 | — | — | |
| SCHEMBL859159 | 0.70 | ALDH1A1 (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030105343-A1 | Benzofuran compounds | SHARP KABUSHIKI KAISHA (JP) | 2003-06-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030105343-A1 | Benzofuran compounds | BBOX1, DDO, OGFOD1 | S100B 4817/4885S1PR1 4156/4885MAPT 2517/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.