Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.49 |
| ▸ | ELANE | P08246 | 4/20 | 0.45 |
| ▸ | HTR6 | P50406 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
| ▸ | HTR1F | P30939 | 1/20 | 0.43 |
| ▸ | HTR7 | P34969 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | THRB | P10828 | 1/20 | 0.40 |
| ▸ | TSPO | P30536 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.36 |
| ▸ | LTB4R | Q15722 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6918827 | 0.87 | HTR6 (0.44) | ELANEHTR6HTR1AHTR1DHTR1B | |
| SCHEMBL6820240 | 0.84 | HTR6 (0.52) | DYRK1AELANEHTR6HTR1AHTR1D | |
| SCHEMBL7130815 | 0.78 | ELANE (0.47) | DYRK1AELANEHTR6HTR1AHTR1D | |
| SCHEMBL6922117 | 0.76 | ELANE (0.43) | DYRK1AELANETSPONPSR1TSHR | |
| SCHEMBL6972524 | 0.73 | HTR6 (0.77) | DYRK1AELANEHTR6HTR1AHTR1D | |
| SCHEMBL7063772 | 0.72 | HTR7 (0.45) | DYRK1AHTR6HTR1AHTR1DHTR1B | |
| SCHEMBL6820991 | 0.71 | HTR6 (0.52) | HTR6HTR1AHTR1DHTR1BHTR1F | |
| SCHEMBL6817332 | 0.70 | HTR6 (0.70) | ELANEHTR6HTR1AHTR1DHTR1B | |
| SCHEMBL6817355 | 0.69 | HTR6 (0.52) | DYRK1AHTR6HTR1AHTR1DHTR1B | |
| SCHEMBL3557948 | 0.68 | ALDH1A1 (0.44) | HTR7KMT2AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004048331-A1 | N-ARYLALKYL-3-AMINOALKOXYINDOLES AND THEIR USE AS 5-HT LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2004-06-10 | — | — | WO | claimed |