Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 7/20 | 0.48 |
| ▸ | MME | P08473 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | CNR1 | P21554 | 1/20 | 0.44 |
| ▸ | CTSG | P08311 | 1/20 | 0.43 |
| ▸ | CMA1 | P23946 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.43 |
| ▸ | KDM4A | O75164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7068105 | 0.88 | EPHX2 (0.47) | EPHX2MMECNR1CTSGCMA1 | |
| SCHEMBL7068109 | 0.84 | EPHX2 (0.47) | EPHX2KMT2AALDH1A1HPGDCYP2D6 | |
| SCHEMBL7068112 | 0.84 | EPHX2 (0.47) | EPHX2KMT2AALDH1A1HPGDCYP2D6 | |
| SCHEMBL7982890 | 0.82 | ACE (0.52) | MMEKMT2AALDH1A1HPGDCYP2D6 | |
| SCHEMBL7982892 | 0.82 | ACE (0.52) | MMEKMT2AALDH1A1HPGDCYP2D6 | |
| SCHEMBL7982632 | 0.81 | MMP1 (0.49) | HPGDCTSGCMA1 | |
| SCHEMBL27522992 | 0.81 | MMP1 (0.49) | HPGDCTSGCMA1 | |
| SCHEMBL27550386 | 0.80 | MMP1 (0.46) | EPHX2KMT2AALDH1A1HPGDCYP2D6 | |
| SCHEMBL7067649 | 0.78 | CTSG (0.56) | MMEHPGDCTSGCMA1 | |
| SCHEMBL7067645 | 0.78 | CTSG (0.56) | MMEHPGDCTSGCMA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6277876-B1 | Matrix metalloproteinase inhibitors | LEO PHARMACEUTICAL PRODUCTS LTD. A/S (DK) | 2001-08-21 | — | — | US | disclosed |