Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN1A | P35498 | 2/20 | 0.43 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.43 |
| ▸ | SCN8A | Q9UQD0 | 2/20 | 0.43 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 4/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.42 |
| ▸ | SCN3A | Q9NY46 | 2/20 | 0.41 |
| ▸ | SCN4A | P35499 | 1/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.41 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.41 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7132373 | 0.89 | SCN1A (0.46) | SCN1ASCN5ASCN8ASCN1BMEN1 | |
| SCHEMBL7078927 | 0.81 | CA12 (0.44) | MEN1KMT2ASCN3AALDH1A1HTT | |
| SCHEMBL7074308 | 0.80 | MMP13 (0.45) | KMT2AALDH1A1HTTGAAMMP13 | |
| SCHEMBL7078046 | 0.80 | DHODH (0.42) | ALDH1A1HSD17B10MAPTLMNAMMP13 | |
| SCHEMBL7077769 | 0.75 | HSD17B10 (0.39) | KMT2AALDH1A1HSD17B10GAAMMP13 | |
| SCHEMBL7074900 | 0.73 | F2 (0.45) | KMT2AALDH1A1LMNAGAAPOLB | |
| SCHEMBL7073767 | 0.72 | MMP13 (0.49) | MEN1KMT2AALDH1A1CYP2C9CYP2C19 | |
| SCHEMBL7077549 | 0.71 | DHODH (0.44) | ALDH1A1MAPTLMNACYP2C9 | |
| SCHEMBL7135328 | 0.70 | GCK (0.47) | KMT2ALMNAGAAPOLBSMN1; SMN2 | |
| SCHEMBL10625612 | 0.70 | PLA2G7 (0.51) | MEN1KMT2AALDH1A1PKMHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003059872-A1 | AVB3 AND AVB5 INTEGRIN ANTAGONISTS AND METHODS OF TREATING DISEASES OR CONDITIONS ASSOCIATED WITH AVB3 AND AVB5 INTEGRINS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-07-24 | — | — | WO | disclosed |
| WO-2003059872-A1 | AVB3 AND AVB5 INTEGRIN ANTAGONISTS AND METHODS OF TREATING DISEASES OR CONDITIONS ASSOCIATED WITH AVB3 AND AVB5 INTEGRINS | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-07-24 | — | — | WO | disclosed |