⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7142863 | 0.68 | LMNA (0.34) | — | |
| SCHEMBL7150130 | 0.62 | CTSS (0.32) | — | |
| SCHEMBL756292 | 0.56 | LMNA (0.45) | — | |
| SCHEMBL918533 | 0.56 | — | — | |
| SCHEMBL11588095 | 0.55 | LMNA (0.43) | — | |
| SCHEMBL11590303 | 0.55 | LMNA (0.43) | — | |
| SCHEMBL11037569 | 0.55 | THRB (0.46) | — | |
| SCHEMBL6738852 | 0.54 | AOC3 (0.41) | — | |
| SCHEMBL8587190 | 0.53 | KDM4E (0.43) | — | |
| SCHEMBL8403351 | 0.53 | KDM4E (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030065146-A1 | Monomeric diols, phosphate linked oligomers formed therefrom and processes for preparing | COOK PHILLIP D (US) | 2003-04-03 | — | — | US | disclosed |
| US-6448373-B1 | INHIBITORS OF ENZYMES SUCH AS PHOSPHOLIPASE A2; TREATMENT OF INFLAMMATORY DISEASES INCLUDING ATOPIC DERMATITIS AND INFLAMMATORY BOWEL DISEASE | ISIS PHARMACEUTICALS, INC. | 2002-09-10 | — | — | US | disclosed |
| EP-0739351-B1 | MONOMERIC DIOLS AND PHOSPHATE LINKED OLIGOMERS FORMED THEREFROM | ISIS PHARMACEUTICALS INC (US) | 2002-04-10 | — | — | EP | disclosed |