Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | NAMPT | P43490 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 2/20 | 0.49 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.44 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.44 |
| ▸ | RELA | Q04206 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL6282388 | 0.99 | RAB9A (0.52) | RAB9ANPC1NAMPTALDH1A1MAPT | |
| SCHEMBL7142799 | 0.84 | NAMPT (0.49) | RAB9ANPC1NAMPTALDH1A1MAPT | |
| Bromide SCHEMBL6276160 | 0.83 | NAMPT (0.48) | RAB9ANPC1NAMPTALDH1A1MAPT | |
| SCHEMBL7144741 | 0.82 | ALDH1A1 (0.44) | RAB9ANPC1NAMPTALDH1A1MAPT | |
| SCHEMBL7149156 | 0.82 | CYP17A1 (0.49) | RAB9AALDH1A1MAPTLMNAHTT | |
| SCHEMBL7140967 | 0.82 | SMN1; SMN2 (0.51) | NAMPTALDH1A1LMNAHTTSMN1; SMN2 | |
| SCHEMBL7144713 | 0.81 | CYP19A1 (0.53) | RAB9ANPC1NAMPTALDH1A1MAPT | |
| SCHEMBL7149214 | 0.81 | POLB (0.51) | RAB9AALDH1A1LMNATHRBSMN1; SMN2 | |
| Bromide SCHEMBL6279795 | 0.81 | CYP17A1 (0.48) | RAB9ANPC1ALDH1A1MAPTLMNA | |
| Bromide SCHEMBL6280874 | 0.81 | ALDH1A1 (0.43) | RAB9ANPC1NAMPTALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6620825-B1 | 1,3-Azole compound substituted by pyridyl; administering as antiasthmatic, antiinflammatory or antiallergen agents | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-09-16 | — | — | US | disclosed |
| US-6436966-B1 | Adenosine A3 receptor antagonists | TAKEDA CHEMICAL IND., LTD. (JP) | 2002-08-20 | — | — | US | disclosed |