Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | MGLL | Q99685 | 2/20 | 0.41 |
| ▸ | NPY2R | P49146 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6450860 | 0.86 | GAA (0.41) | FAAHMGLLNPY2RGAAPOLB | |
| SCHEMBL1244496 | 0.78 | TRPA1 (0.47) | FAAHMGLLGAAPOLBALDH1A1 | |
| SCHEMBL6447767 | 0.78 | LSS (0.41) | FAAHMGLLNPY2RGAAALDH1A1 | |
| SCHEMBL7145847 | 0.77 | LSS (0.45) | FAAHMGLLNPY2RGAATRPA1 | |
| SCHEMBL2618043 | 0.76 | GAA (0.51) | FAAHMGLLNPY2RGAAPOLB | |
| SCHEMBL7142947 | 0.76 | LSS (0.39) | FAAHMGLLGAAALDH1A1TRPA1 | |
| SCHEMBL7144981 | 0.76 | GPR119 (0.47) | KDM4E | |
| SCHEMBL7142436 | 0.76 | LSS (0.46) | MGLLNPY2RGAA | |
| SCHEMBL10458902 | 0.72 | GAA (0.72) | GAAPOLBALDH1A1SMN1; SMN2TRPA1 | |
| SCHEMBL7039131 | 0.71 | LSS (0.47) | FAAHMGLLGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1317432-A1 | PIPERIDINE DERIVATIVES FOR USE AS 2,3-OXIDOSQUALENE-LANOSTEROL CYCLASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-06-11 | — | — | EP | disclosed |
| WO-2002020483-A1 | PIPERIDINE DERIVATIVES FOR USE 2,3-OXIDOSQUALENE-LANOSTEROL CYCLASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2002-03-14 | — | — | WO | disclosed |