Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.39 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.39 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.38 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.38 |
| ▸ | CDK2 | P24941 | 3/20 | 0.38 |
| ▸ | CDK1 | P06493 | 2/20 | 0.38 |
| ▸ | CDK4 | P11802 | 2/20 | 0.38 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.38 |
| ▸ | CCND1 | P24385 | 2/20 | 0.38 |
| ▸ | CDK7 | P50613 | 2/20 | 0.38 |
| ▸ | CCNH | P51946 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7149809 | 0.83 | ALDH1A1 (0.43) | LMNAADORA2AADORA1PRKDCKDM4E | |
| SCHEMBL7149801 | 0.77 | PIP4K2A (0.44) | ADORA2AADORA1PRKDCKDM4EHSD17B10 | |
| SCHEMBL7166270 | 0.74 | SRC (0.48) | LMNAADORA2AADORA1PRKDCCCNA2 | |
| SCHEMBL7202387 | 0.71 | JAK1 (0.44) | LMNAADORA2AADORA1KDM4EHSD17B10 | |
| SCHEMBL16618011 | 0.68 | LMNA (0.45) | LMNAKDM4EHPGDALDH1A1MAPT | |
| SCHEMBL7913437 | 0.65 | LMNA (0.51) | LMNAADORA2AADORA1KDM4EHSD17B10 | |
| SCHEMBL5209830 | 0.65 | TGFBR1 (0.52) | KDM4EHSD17B10RXFP1HPGDALDH1A1 | |
| SCHEMBL27470171 | 0.65 | ADORA2A (0.58) | LMNAADORA2AADORA1KDM4EHSD17B10 | |
| SCHEMBL5208695 | 0.64 | ACVR1 (0.53) | KDM4ERXFP1ALDH1A1ADRA2AMAPT | |
| Hydrochloric Acid SCHEMBL5210606 | 0.63 | ACVR1 (0.52) | KDM4ERXFP1ALDH1A1ADRA2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1268431-A1 | 3-CYANOQUINOLINES,3-CYANO-1,6-NAPHTHYRIDINES, AND 3-CYANO-1,7-NAPHTHYRIDINES AS PROTEIN KINASE INHIBITORS | Wyeth (US) | 2003-01-02 | — | — | EP | disclosed |
| WO-2001072711-A1 | 3-CYANOQUINOLINES,3-CYANO-1,6-NAPHTHYRIDINES, AND 3-CYANO-1,7-NAPHTHYRIDINES AS PROTEIN KINASE INHIBITORS | WYETH (US) | 2001-10-04 | — | — | WO | disclosed |