Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | F2 | P00734 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.41 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | PGR | P06401 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.40 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6763307 | 0.85 | L3MBTL1 (0.71) | L3MBTL1ATMTDP1NPSR1KMT2A | |
| SCHEMBL6265347 | 0.79 | ATM (0.63) | L3MBTL1ATMTDP1F2NPSR1 | |
| SCHEMBL27639141 | 0.76 | TDP1 (0.50) | L3MBTL1ATMTDP1NPSR1PARP10 | |
| SCHEMBL29624301 | 0.76 | PARP15 (0.46) | PARP15PARP10PARP2KMT2AMEN1 | |
| Carbamic Acid Phenyl Ester SCHEMBL28143567 | 0.75 | TSHR (0.52) | L3MBTL1F2PARP15PARP10PARP2 | |
| SCHEMBL5650101 | 0.74 | RAB9A (0.59) | L3MBTL1ATMTDP1NPSR1KMT2A | |
| SCHEMBL4814349 | 0.73 | ALDH1A1 (0.58) | L3MBTL1TDP1F2PARP15PARP10 | |
| SCHEMBL3868314 | 0.73 | CHRNB2 (0.41) | PARP15PARP10PARP2KMT2APGR | |
| SCHEMBL14698064 | 0.73 | KMT2A (0.54) | L3MBTL1ATMTDP1NPSR1KMT2A | |
| SCHEMBL30100512 | 0.72 | KMT2A (0.61) | L3MBTL1ATMPARP15PARP10PARP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6657083-B2 | Photographic couplers; acylation amine group in position 2 | EASTMAN KODAK COMPANY | 2003-12-02 | — | — | US | disclosed |
| US-6613943-B2 | Intermediates for 4-substituted-2,5-diaminophenol derivatives as phenolic cyan couplers for color photography; deblocking the 2-acyl group by hydrolysis | EASTMAN KODAK COMPANY | 2003-09-02 | — | — | US | disclosed |
| US-20030109716-A1 | 5-ACYLAMINO-2-AMINO-4-SUBSTITUTED-PHENOL COMPOUNDS AND METHOD OF USING THEM | EASTMAN KODAK COMPANY | 2003-06-12 | — | — | US | disclosed |
| US-20030109753-A1 | 4-acylamino-2-hydroxy-5-substituted-acylanilide compounds and method of using them | EASTMAN KODAK COMPANY | 2003-06-12 | — | — | US | disclosed |
| EP-1316544-A1 | 5-acylamino-2-amino-4-substituted-phenol compounds and method of using them | EASTMAN KODAK COMPANY (US) | 2003-06-04 | — | — | EP | disclosed |
| EP-1316550-A1 | 6-Acylamino-5-substituted-benzoxazol-2-one compounds and method for using them | EASTMAN KODAK COMPANY (US) | 2003-06-04 | — | — | EP | disclosed |
| US-6525219-B1 | Chemical intermediates for cyan dye forming couplers; deblocking, hydrolysis, acylation | EASTMAN KODAK COMPANY | 2003-02-25 | — | — | US | disclosed |
| US-6515176-B1 | Disclosed is a 6-acylamino-5-substituted-benzoxazol-2-one compound having the structural formula I: Also disclosed is a method for forming a cyan dye-forming coupler from the above compound. The method and intermediate with a simplified | EASTMAN KODAK COMPANY | 2003-02-04 | — | — | US | disclosed |
| US-6482953-B1 | 2-benzyloxy-4-nitro-5-substituted-acylanilide compounds and method of using them | EASTMAN KODAK COMPANY | 2002-11-19 | — | — | US | disclosed |
| US-6482985-B1 | 2-benzyloxy-5-halo-acylanilide compounds and method of using them | EASTMAN KODAK COMPANY | 2002-11-19 | — | — | US | disclosed |
| US-6476202-B1 | 5-acylamino-2-arylazo, nitro, or nitroso-4-substituted-phenol compounds and method of using them | EASTMAN KODAK COMPANY | 2002-11-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030109753-A1 | 4-acylamino-2-hydroxy-5-substituted-acylanilide compounds and method of using them | CBR3, AADAC, HAAO | L3MBTL1 4494/4885ATM 4320/4885TDP1 2540/4885 |
| US-20030109716-A1 | 5-ACYLAMINO-2-AMINO-4-SUBSTITUTED-PHENOL COMPOUNDS AND METHOD OF USING THEM | AADAT, AAAS, ANXA7 | L3MBTL1 4106/4885ATM 1566/4885TDP1 1569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.